201402-95-1

Basic information

• Product Name: Acetic acid 3-{(S)-4-[(S)-1-hydroxy-2-(toluene-4-sulfonyloxy)-ethyl]-4,5-dihydro-oxazol-2-yl}-2-methyl-phenyl ester
• Synonyms: Acetic acid 3-{(S)-4-[(S)-1-hydroxy-2-(toluene-4-sulfonyloxy)-ethyl]-4,5-dihydro-oxazol-2-yl}-2-methyl-phenyl ester
• CAS NO: 201402-95-1
• Molecular Weight: 433.482
• Mol File: 201402-95-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetic acid 3-{(S)-4-[(S)-1-hydroxy-2-(toluene-4-sulfonyloxy)-ethyl]-4,5-dihydro-oxazol-2-yl}-2-methyl-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid 3-{(S)-4-[(S)-1-hydroxy-2-(toluene-4-sulfonyloxy)-ethyl]-4,5-dihydro-oxazol-2-yl}-2-methyl-phenyl ester(201402-95-1)
• EPA Substance Registry System: Acetic acid 3-{(S)-4-[(S)-1-hydroxy-2-(toluene-4-sulfonyloxy)-ethyl]-4,5-dihydro-oxazol-2-yl}-2-methyl-phenyl ester(201402-95-1)

Safety Data

• Hazardous Substances Data: 201402-95-1(Hazardous Substances Data)

Upstream product

• 167678-46-8 3-acetoxy-2-methylbenzoyl chloride 
• 50623-73-9 (2R,3R)-2,3-dihydroxy-4-{[(4-methylphenyl)sulfonyl]oxy}butyl 4-methyl-1-benzenesulfonate 
• 231607-42-4 C₁₈H₂₀O₉S₃ 
• 231607-41-3 C₁₈H₂₁N₃O₇S₂ 
• 201402-92-8 C₁₈H₂₀O₁₀S₃ 
• 51064-65-4 1,4-di-o-tosyl-2,3-isopropylidene-D-threitol 

Downstream Products

• 159989-64-7 nelfinavir 
• 188936-07-4 (3S,4aS,8aS)-N-tert-butyl-2-((R)-2-hydroxy-2-((S)-2-(3-hydroxy-2-methylphenyl)-4,5-dihydrooxazol-4-yl)ethyl)-decahydroisoquinoline-3-carboxamide 

Relevant articles and documents

A synthesis of the HIV-protease inhibitor nelfinavir from D-tartaric acid

This letter describes a new synthesis of the HIV-protease inhibitor nelfinavir. The synthesis features a selective opening of a D-tartaric acid-derived cyclic sulfate with nitrogen nucleophiles.