201405-69-8Relevant academic research and scientific papers
Microwave-Promoted Pd-Catalyzed Synthesis of Dibenzofurans from Ortho-Arylphenols
Schmidt, Bernd,Riemer, Martin
, p. 1287 - 1297 (2017)
ortho-Aryl phenols, synthesized via protecting group free Suzuki–Miyaura coupling of ortho-halophenols and arene boronic acids, undergo a cyclization to dibenzofurans via oxidative C–H activation. The reaction proceeds under microwave irradiation in short reaction times using catalytic amounts of Pd(OAc)2 without additional ligands.
Synthesis of orthogonally protected biaryl amino acid derivatives
Moreno, Eduardo,Nolasco, Luca Antonio,Caggiano, Lorenzo,Jackson, Richard F. W.
, p. 3639 - 3647 (2008/09/20)
The efficient and direct synthesis of protected biaryl amino acids, including dityrosine (50% overall yield over 3 steps), by Negishi cross-coupling of the serine-derived organozinc reagent 4 with iodo- and di-iodobiaryls, is reported. An improved, althou
