20157-74-8

Usage

Uses

Used in Organic Synthesis:
(PENTAFLUOROETHYL)DIPHENYLPHOSPHINE is used as a ligand in various organic synthesis reactions, particularly in transition metal-catalyzed processes. Its role in these reactions is crucial for enhancing the efficiency and selectivity of the synthesis, leading to the production of a wide range of chemical compounds.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, (PENTAFLUOROETHYL)DIPHENYLPHOSPHINE serves as a key component in the synthesis of biologically active compounds. Its unique properties allow it to contribute to the development of new drugs and pharmaceuticals, potentially offering novel treatments and therapeutic options.
Used as a Precursor for Phosphine Derivatives:
(PENTAFLUOROETHYL)DIPHENYLPHOSPHINE is also utilized as a precursor in the preparation of other phosphine derivatives. This makes it an essential building block in the synthesis of a variety of phosphorus-containing compounds, which have applications in various chemical and industrial processes.
Used in Organometallic Chemistry:
Within the field of organometallic chemistry, (PENTAFLUOROETHYL)DIPHENYLPHOSPHINE is employed as a ligand for metal complexes. Its unique structure allows it to form stable and functional organometallic compounds, which are important in various chemical transformations and reactions.
Used in Catalysis:
(PENTAFLUOROETHYL)DIPHENYLPHOSPHINE plays a significant role in catalysis, especially in palladium-catalyzed coupling reactions. Its presence as a ligand can improve the catalytic activity and selectivity of these reactions, leading to more efficient and cleaner chemical processes.

Upstream product

• 76-15-3 Chloropentafluoroethane 
• 1079-66-9 chloro-diphenylphosphine 
• 354-64-3 Pentafluoroethyl iodide 
• 17154-34-6 (trimethylsilyl)diphenylphosphine 
• 20157-72-6 Pentafluorpropionyl-diphenylphosphin 
• 4376-01-6 sodium diphenylphosphide 
• 13360-92-4 phenyl diphenylphosphinite 
• 124898-13-1 trimethyl(pentafluoroethyl)silane 

Downstream Products

• 717832-47-8 trans-(pentafluoroethyldiphenylphosphine)2PtCl₂ 
• 847228-56-2 Cr(CO)5((pentafluoroethyl)diphenylphosphine) 

Relevant academic research and scientific papers

Fluoroalkenyl, fluoroalkynyl and fluoroalkyl phosphines

A review of the methods available for the preparation of monodentate P(III) compounds containing fluoroalkenyl, fluoroalkynyl and fluoroalkyl groups is given. The synthesis, properties and coordination chemistry of some fluoroalkenyl- and fluoroalkynyl-co

A generic route to fluoroalkyl-containing phosphanes

The reaction of trimethylsilyl-containing phosphanes with perfluoroiodoalkanes provides a general and convenient route to perfluoroalkyl-containing phosphanes. The Royal Society of Chemistry 2009.

The synthesis of tris(perfluoroalkyl)phosphines

Tris(perfluoroalkyl)phosphines, of interest as turtable alternatives to the carbon monoxide ligand, can be synthesised by the nucleophile mediated reaction of perfluoroalkyltrimethylsilanes with triphenylphosphite; the method can be extended to diphosphines. The Royal Society of Chemistry 2005.

Perfluoroalkylphosphine coordination chemistry of platinum: Synthesis of (C2F5)2PPh and (C2F 5)PPh2 complexes of platinum(II)

A 1: 1 addition of Ph2PCl to an ethereal solution of C 2F5Li (formed from the reaction of BuLi with C 2F5C1) yields Ph2P(C2F5) (abbreviated pfepp) (1). The introduction of a fluoroethyl group results in a phosphine with electronic characteristics that approximate phosphites, bridging the electronic gap between traditional donor phosphine ligands and more electrophilic phosphine ligands like PhP(C2F5)2 (2). The pfepp ligand 1 is isolated as a high boiling liquid, which crystallizes upon standing at room temperature in an inert atmosphere. A series of Pt(u) complexes of the type trans-L2PtCl2 (L = pfepp 3; PhP(C2F5)2 4) have been prepared and structurally characterized by multinuclear NMR, IR and X-ray crystallography. The crystal structure of 1 is the first example of a structurally characterized monodentate phosphine with a pentafluoroethyl pendant group.