201669-68-3

Upstream product

• 76-83-5 trityl chloride 
• 201669-67-2 (E)-1-((1S,5R,7R)-10,10-Dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-3-(1H-imidazol-4-yl)-propenone 
• 3465-72-3 urocanic Acid 
• 94594-90-8 (2R)-bornane-10,2-sultam 

Downstream Products

• 201669-70-7 ((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-[(1R,2R)-2-(1-trityl-1H-imidazol-4-yl)-cyclopropyl]-methanone 
• 201669-69-4 ((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-[(1S,2S)-2-(1-trityl-1H-imidazol-4-yl)-cyclopropyl]-methanone 
• 201669-71-8 (1S,2S)-1-(1-triphenylmethyl-1H-imidazol-4-yl)cyclopropane-2-carboxylic acid 
• 201669-72-9 (1R,2R)-1-(1-triphenylmethyl-1H-imidazol-4-yl)cyclopropane-2-carboxylic acid 

Relevant academic research and scientific papers

Diastereoselective synthesis of trans-2-(1-triphenylmethyl-1H-imidazol-4-yl)cyclopropanecarboxylic acids: Key intermediates for the preparation of potent and chiral histamine H3 receptor agents

Procedures for the preparation of both enantiomers of trans-2-(1-triphenylmethyl-1H-imidazol-4-yl)-cyclopropanecarboxylic acid are described. The key step in the synthesis is a 3:1 diastereoselective cyclopropanation of (5R)-trans-4-aza-10,10-dimethyl-3-t