Bioorganic and Medicinal Chemistry Letters p. 3017 - 3022 (1997)
Update date:2022-07-29
Topics:
Khan, M. Amin
Yates, Stephen L.
Tedford, Clark E.
Kirschbaum, Kristin
Phillips, James G.
Procedures for the preparation of both enantiomers of trans-2-(1-triphenylmethyl-1H-imidazol-4-yl)-cyclopropanecarboxylic acid are described. The key step in the synthesis is a 3:1 diastereoselective cyclopropanation of (5R)-trans-4-aza-10,10-dimethyl-3-t
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