201678-25-3Relevant academic research and scientific papers
Diastereoselective formal synthesis of the antifungal agent, (+)- Preussin. A new entry to chiral pyrrolidines
Armas, Pedro De,Garcia-Tellado, Fernando,Marrero-Tellado, Jose J.,Robles, Juana
, p. 131 - 134 (1998)
A formal total synthesis of (+)-Preussin was achieved by using D- mannose as the starting material. The key step involved diastereoselective addition of allyltrimethylsilane to the bicyclic ketal 5.
