20168-75-6

Upstream product

• 21969-11-9 1-(4-chlorophenylthio)-4-nitrobenzene 
• 937-32-6 4-nitrobenzenesulfenyl chloride 
• 58175-41-0 4-chloro-phenylmercury ⁽¹⁺⁾; thiophenolate 
• 1142-19-4 4,4'-dichlorodiphenyl disulfide 
• 1849-36-1 para-nitrobenzenethiol 
• 106-54-7 p-Chlorothiophenol 
• 14204-31-0 2-(4-chlorophenylthio)isoindoline-1,3-dione 
• 88683-47-0 2-((4-nitrophenyl)thio)isoindoline-1,3-dione 
• 100-32-3 di(p-nitrophenyl) disulfide 
• 60199-37-3 N-benzoyl p-nitrobenzenesulfenamide 
• 106119-09-9 C₁₇H₁₇N₃O₄S 

Downstream Products

• 116206-72-5 C₂₄H₁₈ClN₃O₆S₄ 

Relevant academic research and scientific papers

NFSI-catalyzed S[sbnd]S bond exchange reaction for the synthesis of unsymmetrical disulfides

The metal-free S[sbnd]S bond exchange reaction of symmetrical disulfides catalyzed by NFSI is described. This novel protocol provides a facile and efficient approach to accessing important unsymmetrical disulfides. Furthermore, this strategy could also be utilized in the late-stage functionalization of amino acids, drugs, and natural products. The broad substrate scope, good functional group tolerance and easy accessibility of catalyst indicate that this strategy affords a green and practical complementary method to various unsymmetrical disulfides.

Unsymmetrical Disulfides Synthesis via Sulfenium Ion

An umpolung approach for the synthesis of unsymmetrical disulfides via sulfenium ion is reported. In situ generated electrophilic sulfenium ion from electron-rich thiols reacted with second thiols to yield unsymmetrical disulfides. Using an iodine catalyst and 4-dimethylaminopyridine (DMAP)/water as promoter, the target syntheses were achieved in one pot under aerobic condition.

Microwave-assisted synthesis of disulfides

A new microwave-assisted synthesis methodology for the preparation of substituted disulfide derivatives is presented. 4-Substituted sulfenimides were reacted with 4-substituted thiols under neat (to right doughy consistency) conditions in chloroform, with both microwave heating and conventional methods. The resulting 4-substituted disulfide derivatives were obtained at higher yields and in shorter reaction times with microwave heating. Their chemistry was confirmed by 1H-NMR, 13C-NMR, infrared (IR), and elemental analysis.

Unsymmetrical aryl disulfides with excellent transparency in the visible region for second order nonlinear optics

Several unsymmetrically substituted aromatic donor-acceptor disulfides have been synthesized and analysed for their second order nonlinear optical properties. These molecules exhibit moderately high first hyperpolarizability (β) with excellent transparenc

REACTION OF ARENESULFINIMIDIC ACID DERIVATIVES WITH THIOPHENOLS

The amides and esters of N-substituted arenesulfinimidic acids are reduced by the action of thiophenols primarily to N-substituted arenesulfenamides, while the thiophenols are oxidized to the corresponding derivatives of the arenesulfinic acids.

REACTIONS OF 4-NITROPHENYL-SUBSTITUTED PHENYL SU ES AND RELATED COMPOUNDS WITH ELEMENTAL SULFUR IN LIQUID AMMONIA: FORMATION OF UNSYMMETRICAL AROMATIC DISULFIDES

Various unsymmetrical disulfides in addition to symmetrical disulfides were obtained in moderate yields by the reactions of 4-nitrophenyl-substituted phenyl sulfides and related compounds such as S-4-nitrophenyl S-substituted phenyl sulfimides and sulfodi