201735-87-7Relevant academic research and scientific papers
Synthesis and hybridization studies of a 5-aminopentanoic acid nucleobase (APN) dimer
Donaldson, Susan F.,Bergmeier, Stephen C.,Hines, Jennifer V.,Gerdeman, Melinda S.
, p. 111 - 123 (2007/10/03)
We have prepared a 5-aminopentanoic acid nucleobase (APN) dimer and investigated its hybridization capabilities to complementary DNA using both UV melting and NMR techniques.
Synthesis and antiviral activity of novel aza-acyclonucleosides
Bergmeier, Stephen C.,Fundy, Susan L.,Drach, John C.
, p. 227 - 238 (2007/10/03)
We have prepared a series of novel aza-acyclonucleosides as potential antiviral agents. These compounds were prepared from diethanolamine and the desired purine or pyrimidine base via a Mitsunobu coupling. No antiviral activity was observed against either
Synthesis of oligo(5-aminopentanoic acid)-nucleobases (APN): Potential antisense agents
Bergmeier, Stephen C.,Fundy, Susan L.
, p. 3135 - 3138 (2007/10/03)
Oligomers of 5-amino pentanoic acid nucleobases have been prepared for use as antisense agents. The synthesis of the 5'-end starter unit and the 3'-end monomer unit, as well as the coupling procedures used for oligomer formation are described.
