Cas 20178-22-7,1H-Pyrrole-3-carboxylic acid, 2,5-dihydro-4-hydroxy-1-methyl-5-oxo-2-phenyl-, ethyl ester

20178-22-7

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Basic information

Product Name: 1H-Pyrrole-3-carboxylic acid, 2,5-dihydro-4-hydroxy-1-methyl-5-oxo-2-phenyl-, ethyl ester
Synonyms:
CAS NO:20178-22-7
Molecular Formula: C14H15NO4
Molecular Weight: 261.277
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 1H-Pyrrole-3-carboxylic acid, 2,5-dihydro-4-hydroxy-1-methyl-5-oxo-2-phenyl-, ethyl ester(CAS DataBase Reference)
NIST Chemistry Reference: 1H-Pyrrole-3-carboxylic acid, 2,5-dihydro-4-hydroxy-1-methyl-5-oxo-2-phenyl-, ethyl ester(20178-22-7)
EPA Substance Registry System: 1H-Pyrrole-3-carboxylic acid, 2,5-dihydro-4-hydroxy-1-methyl-5-oxo-2-phenyl-, ethyl ester(20178-22-7)

Safety Data

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Safety Statements: N/A
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HazardClass: N/A
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Hazardous Substances Data: 20178-22-7(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 20178-22-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,1,7 and 8 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 20178-22:
(7*2)+(6*0)+(5*1)+(4*7)+(3*8)+(2*2)+(1*2)=77
77 % 10 = 7
So 20178-22-7 is a valid CAS Registry Number.

20178-22-7Upstream product

20178-22-7Downstream Products

20178-22-7Relevant academic research and scientific papers

Synthesis and bioactivity of some 2-oxo-5-aryl-3-hydrazone and 2-oxo-5-aryl-4-hydrazone pyrrolidine derivatives

Mohammat, Mohd Fazli,Najim, Nigar,Mansor, Nurul Shulehaf,Sarman, Sharil,Shaameri, Zurina,Zain, Mazatulikhma Mat,Hamzah, Ahmad Sazali

experimental part, p. 429 - 438 (2011/12/05)

2-Aryl-4,5-dioxopyrrolidine-3-carboxylate and 5-aryl-2,4-dioxopyrrolidine- 3-carboxylate derivatives were successfully synthesized via carbonyl-based multiple component reaction and Dieckmann cyclization, respectively. Successive functional group transformations which include decarboxylation and hydrazonation afforded 2-oxo-5-aryl-3-hydrazone and 2-oxo-5-aryl-4-hydrazone derivatives. Compound 3d exhibited activity against human histiocytic lymphoma (U937) and neuroblastoma (SH-SY5Y) cell lines while compound 6 showed neuroprotective ability from oxidative stress medium induced with H2O2.

Synthesis of 2,3-dioxo-5-(substituted)arylpyrroles and their 2-oxo-5-aryl-3-hydrazone pyrrolidine derivatives

Mohammat,Shaameri,Hamzah

experimental part, p. 250 - 256 (2009/08/15)

Some novel 2,3-dioxo-5-(substituted)arylpyrroles have been synthesized. Among these, pyrrolidine compound 1b was converted to 2,3-dioxo-5-aryl pyrrolidine 2b. Finally a set of hydrazone derivatives was obtained from the reaction of 2b with various hydrazi

Synthesis of 5-aryl-2-oxopyrrole derivatives as synthons for highly substituted pyrroles

Metten, Bert,Kostermans, Maarten,Van Baelen, Gitte,Smet, Mario,Dehaen, Wim

, p. 6018 - 6028 (2007/10/03)

A small library of 2-oxo-5-(hetero)arylpyrroles was prepared starting from 2,3-dioxo-5-(hetero)arylpyrrolidines. The large synthetic possibilities of these 2-oxopyrroles were investigated. The 2-oxopyrroles offer a large number of possible derivatizations

SYNTHESIS OF 2,3-DIALKOXY-1H-PYRROLE VIA REDUCTION OF DIOXOPYRROLINE WITH SODIUM HYDROSULFITE

Sano, Takehiro,Seki, Masaharu,Toda, Jun,Tsuda, Yoshisuke

, p. 2541 - 2548 (2007/10/02)

Reduction of 1H-pyrrole-2,3-dione (3 and 7) with sodium hydrosulfite took place selectively in a 1,4-manner.Methylation of the product with diazomethane gave 1,5-dihydro-3-methoxy-2H-pyrrol-2-one (5 and 8) in good yield.Treatment of the methyl ether (5 or

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