201800-34-2

Upstream product

• 87316-22-1 1,5-anhydro-6-O-(tert-butyldiphenylsilyl)-2-deoxy-D-lyxo-hex-1-enitol 
• 100-39-0 benzyl bromide 
• 4098-06-0 triacetyl-D-galactal 

Downstream Products

• 365455-25-0 1,5-anhydro-3,4-di-O-benzyl-6-O-tert-butyldiphenylsilyl-2-deoxy-2-nitro-D-lyxo-hex-1-enitol 
• 130323-37-4 (2R,3R,4R)-(3,4-bis(benzyloxy)-3,4-dihydro-2H-pyran-2-yl)methanol 
• 1025795-56-5 C₅₀H₅₀O₈Si 
• 1263477-16-2 2-azido-3,4-di-O-benzyl-6-O-(tert-butyldiphenylsilyl)-2-desoxy-D-galactopyranosylchloride 
• 200998-98-7 Benzoic acid (2R,3R,4S,5S,6R)-4,5-bis-benzyloxy-6-[(2R,3R,4R,5S,6R)-4,5-bis-benzyloxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-hydroxy-tetrahydro-pyran-2-yloxymethyl]-2-(11-methoxycarbonyl-undecyloxy)-tetrahydro-pyran-3-yl ester 
• 200999-00-4 11-methoxycarbonylundecanyl 2-O-benzoyl-6-O-(2-O-benzoyl-3,4-di-O-benzyl-β-D-galactopyranosyl)-3,4-di-O-benzyl-β-D-galactopyranoside 
• 200998-94-3 Benzoic acid (2R,3R,4S,5S,6R)-4,5-bis-benzyloxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-2-(11-methoxycarbonyl-undecyloxy)-tetrahydro-pyran-3-yl ester 
• 200998-93-2 12-[(2R,3R,4R,5S,6R)-4,5-Bis-benzyloxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-hydroxy-tetrahydro-pyran-2-yloxy]-dodecanoic acid methyl ester 
• 200998-95-4 11-methoxycarbonylundecanyl 2-O-benzoyl-3,4-di-O-benzyl-β-D-galactopyranoside 
• 200998-99-8 11-methoxycarbonylundecanyl 2-O-benzoyl-6-O-(2-O-benzoyl-3,4-di-O-benzyl-6-O-tert-butyldiphenylsilyl-β-D-galactopyranosyl)-3,4-di-O-benzyl-β-D-galactopyranoside 
• 116783-35-8 N-(9H-fluoren-9-yl)methoxycarbonyl-O-(3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-α-D-galactopyranosyl)-L-threonine 
• 365455-34-1 N-(tert-butoxycarbonyl)-O-{O-[methyl(5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosyl)onate]-(2->6)-(2-acetamido-3,4-di-O-benzyl-2-deoxy-α-D-galactopyranosyl)}-L-threonine tert-butyl ester 
• 365455-32-9 N-(tert-butoxycarbonyl)-O-{O-[methyl(5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosyl)onate]-(2->6)-(3,4-di-O-benzyl-2-deoxy-2-nitro-α-D-galactopyranosyl)}-L-threonine tert-butyl ester 
• 365455-31-8 N-(tert-butoxycarbonyl)-O-{O-[methyl(5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosyl)onate]-(2->6)-(3,4-di-O-benzyl-2-deoxy-2-nitro-α-D-galactopyranosyl)}-L-serine tert-butyl ester 

Relevant academic research and scientific papers

Synthesis of tetrameric arabinogalactans based on 1,2-anhydrosugars

The spacer-containing tetrameric arabinogalactans 1-3, suitable for CCRC-M7 epitope characterization, are readily accessible by ZnCl2-assisted stepwise elongation of 11-methoxycarbonylundecanol 9 with the 1,2-anhydrogalactose building unit 6. NIS/cat. TfOH-mediated glycosylation of the newly formed 2-OH, 2′-OH, or 2″-OH function in the β-(1→6)-galactoside backbone with the 1-thioarabinofuranoside donor 8, followed by deprotection, provided the target tetramers in high overall yield.

2-nitroglycal and efficient synthesis method thereof

The invention discloses an efficient synthesis method of 2-nitroglycal, and belongs to the technical field of synthesis of sugar. The structure of the 2-nitroglycal is shown in the specification. Secondly, the invention also provides a preparation method of the 2-nitro saccharide alkene, and the preparation method provided by the invention can be used for efficiently preparing the 2-nitroglycal through one-step synthesis.