201849-18-5

Basic information

• Product Name: 5-BROMO-4-CHLORO-2-FLUOROTOLUENE
• Synonyms: 5-BROMO-4-CHLORO-2-FLUOROTOLUENE;5-Bromo-4-chloro-2-fluorotoluene 97%;5-Bromo-4-chloro-2-fluorotoluene97%;1-bromo-2-chloro-4-fluoro-5-methylbenzene
• CAS NO: 201849-18-5
• Molecular Formula: C₇H₅BrClF
• Molecular Weight: 223.47
• Product Categories: Aromatic Halides (substituted);Halogen toluene;Bromine Compounds;Chlorine Compounds;Fluorine Compounds
• Mol File: 201849-18-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 221.8 °C at 760 mmHg
• Flash Point: 87.9 °C
• Appearance: /
• Density: 1.618 g/cm³
• Vapor Pressure: 0.156mmHg at 25°C
• Refractive Index: 1.545
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-BROMO-4-CHLORO-2-FLUOROTOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-4-CHLORO-2-FLUOROTOLUENE(201849-18-5)
• EPA Substance Registry System: 5-BROMO-4-CHLORO-2-FLUOROTOLUENE(201849-18-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 201849-18-5(Hazardous Substances Data)

Usage

General Description

5-Bromo-4-chloro-2-fluorotoluene is a chemical compound that belongs to the class of halogenated toluene derivatives. It is a colorless liquid with a molecular formula C7H5BrClF and a molecular weight of 207.47 g/mol. 5-BROMO-4-CHLORO-2-FLUOROTOLUENE is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also utilized in the production of specialty chemicals and organic synthesis. The presence of bromine, chlorine, and fluorine atoms in its structure makes 5-bromo-4-chloro-2-fluorotoluene a valuable building block for the creation of various functionalized organic compounds. Despite its usefulness, it is important to handle this compound with care due to its potential hazards to human health and the environment.

InChI:InChI=1/C7H5BrClF/c1-4-2-5(8)6(9)3-7(4)10/h2-3H,1H3

Upstream product

• 202865-78-9 2-bromo-5-fluoro 4-methylaniline 

Downstream Products

• 924626-79-9 2-chloro-4-fluoro-5-methylbenzonitrile 
• 208165-96-2 2-chloro-4-fluoro-5-methylbenzoic acid 

Relevant articles and documents

Pyridonecarboxylic acid derivatives or salts thereof and drugs containing the same as the active ingredient

PCT No. PCT/JP97/04326 Sec. 371 Date May 28, 1999 Sec. 102(e) Date May 28, 1999 PCT Filed Nov. 27, 1997 PCT Pub. No. WO98/23592 PCT Pub. Date Jun. 4, 1998The invention relates to pyridonecarboxylic acid derivatives represented by the general formula (1): wherein R1 is -OH, a carboxy-protecting group or (alkyl)amino group, R2 is H, or -NO2, (protected) amino, (protected) hydroxyl, lower alkyl or lower alkoxyl group, R3 is a halogen atom, H, or -NO2, lower alkyl, lower alkoxyl or amino group, R4 is an azido, (substituted) hydrazino, (substituted) amino, lower alkoxyl or hydroxyl group, R5, R6 and R7 are independently H, -NO2, halogen atom or lower alkyl group, R8 is a -NO2, (substituted) amino, -OH or lower alkoxyl group, A is N or C-R12, in which R12 is H, halogen atom, or (substituted) lower alkyl, lower alkenyl, lower alkynyl, lower alkoxyl, lower alkylthio or nitro group, and B is N or C-R13, in which R13 is H or halogen atom, or salts thereof, and medicine comprising such a compound as an active ingredient. The derivatives or the salts thereof exhibit excellent antibacterial action and peroral absorbability, scarcely cause side effects, and are easy of synthesis.