202129-55-3Relevant academic research and scientific papers
Synthesis of aminonicotinonitriles and diaminopyridines through base-catalyzed ring transformation of 2H-pyran-2-ones
Farhanullah,Agarwal, Nidhi,Goel, Atul,Ram, Vishnu Ji
, p. 2983 - 2985 (2007/10/03)
An efficient and convenient synthesis of 2-amino-6-aryl-4-methylsulfanylnicotinonitriles (2), 2-amino-6-aryl-4-substituted-aminonicotinonitriles (4), and 2-amino-6-aryl-4-substituted-aminopyridines (6) has been delineated and illustrated through base-cata
A diversity oriented synthesis of highly functionalized unsymmetrical biaryls through carbanion induced ring transformation of 2H-pyran-2-ones
Agarwal, Nidhi,Saxena, Abhishek S,Farhanullah,Goel, Atul,Ram, Vishnu J
, p. 8793 - 8798 (2007/10/03)
A new route for the synthesis of unsymmetrical biaryls endowed with electron withdrawing and donating substituents is delineated through base catalyzed ring transformation of 2H-pyran-2-ones with malononitrile in a single step. This procedure offers the f
Carbanion-induced base-catalyzed synthesis of unsymmetrical biaryls from suitably functionalized 2H-pyran-2-ones through ring-transformation reactions
Ram, Vishnu Ji,Agarwal, Nidhi
, p. 7127 - 7129 (2007/10/03)
A synthesis of unsymmetrical highly functionalized biaryls with an amino substituent juxtaposed with two nitrile groups in one of the phenyl rings is delineated and illustrated by the carbanion-induced ring-transformation of 6-aryl-4-methylsulfanyl-2H-pyr
Synthetic and mass spectral fragmentation studies on trisubstituted 2H-pyran-2-ones and comparative EIMS behaviour of biologically active 3,5-disubstituted pyrazoles and isoxazoles
Parmar, Virinder S.,Jain, Subhash C.,Jha, Amitabh,Kumar, Naresh,Kumar, Ajay,Vats, Archana,Jha, Hriday N.,Mukherjee, Shubhasish,Singh, Sanjay K.,Jennings, Keith R.,Summerfield, Scott G.,Errington, William,Olsen, Carl E.
, p. 872 - 879 (2007/10/03)
Eight 3-cyano-4-thiomethyl-6-aryl-2H-pyran-2-ones 1-8 and three 3-cyano-4-(N,N-dimethy)amino-6-aryl-2H-pyran-2-ones 9-11 have been synthesised and their detailed mass fragmentation pattern alongwith the X-ray crystal structure of a novel pyrone 5 have been studied. In addition, a comparative EIMS behaviour of 3,5-disubstituted pyrazoles 16-23 and isoxazoles 12-15 is reported. The pyrazole derivative 23 has been found to possess strong anti-invasive activity against human breast carcinoma cells.
