20226-04-4

Usage

Molecular structure

1-benzyl-6,7-dimethoxy-3,4-dihydroisoquinoline has a complex molecular structure, consisting of a 3,4-dihydroisoquinoline core with a benzene ring attached and two methoxy groups at the 6 and 7 positions.

Classification

It is classified as an isoquinoline alkaloid, which is a group of natural products found in various plants.

Benzyl group attachment

The benzyl group is attached to the nitrogen atom of the isoquinoline ring, giving the molecule its unique structure.

Pharmacological properties

1-benzyl-6,7-dimethoxy-3,4-dihydroisoquinoline has been investigated for its potential pharmacological properties, including its potential as an antitumor agent.

Enzyme inhibition

The compound has the ability to inhibit certain enzymes in the body, which may contribute to its potential medicinal properties.

Research and development

Its complex structure and potential medicinal properties make 1-benzyl-6,7-dimethoxy-3,4-dihydroisoquinoline an interesting target for further research and development.

Upstream product

• 67616-16-4 N-[2-(3,4-dimethoxyphenyl)ethyl]benzamide 
• 4876-02-2 N-(3,4-dimethoxyphenethyl)-phenyl acetamide 
• 121089-87-0 N-(4,5-dimethoxy-2-(2-phenylacetyl)phenethyl)acetamide 
• 103-82-2 phenylacetic acid 
• 103-80-0 phenylacetyl chloride 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 

Downstream Products

• 3423-37-8 1-benzyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 20226-05-5 1-benzyl-6,7-dimethoxy-1,2,3,4-tetrahydroisochinoline hydrochloride 

Relevant academic research and scientific papers

Application of differential reactivity towards synthesis of lamellarin and 8-oxoprotoberberine derivatives: Study of photochemical properties of aryl-substituted benzofuran-8-oxoprotoberberines

A unique differential reactivity between dihydroisoquinolines and 3-nitrocoumarins was observed and was exploited for the efficient construction of lamellarins and their isomeric benzofuran-8-oxoprotoberberine derivatives under acid-catalyzed or base-promoted conditions. Further, these prepared aryl-substituted benzofuran-8-oxoprotoberberine derivatives bearing electron-donating substituents on benzofuran moiety are found to be benchtop stable but light-sensitive, and can undergo oxidative ring-opening reaction to give the corresponding keto products when exposed to visible light under aerobic conditions.

STUDIES ON FRIEDEL-CRAFTS ACYLATION OF N-ACETYLHOMOVERATRYLAMINE AND PREPARATION OF 1-SUBSTITUTED 3,4-DIHYDRO-6,7-DIMETHOXYISOQUINOLINES

Friedel-Crafts acylation of N-acetylhomoveratrylamine in a molar ratio of 1:2:3 of 1, AlCl3 and the appropriate acid chloride using nitrobenzene as solvent gave the corresponding 2-acyl derivatives 2a-j in good yields.Subsequent treatment of 2 in boiling

Rearrangement of 1-(α-Hydroxybenzyl)-1,2,3,4-tetrahydroisoquinolines to 1-Phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines

When methoxy-substituted 1-(α-hydroxybenzyl)-1,2,3,4-tetrahydroisoquinolines are heated in formic acid they rearrange initially to give 5-phenyl-2,3-dihydro-1H-3-benzazepines which, on further heating in formic acid, are reduced to 1-phenyl-2,3,4,5-tetrah