62977-82-6

Basic information

• Product Name: Benzeneacetic acid, a-oxo-, phenylmethyl ester
• Synonyms: oxo-phenyl-acetic acid benzyl ester;benzyl-2-oxo-2-phenylacetate;benzyl 2-oxo-2-phenylacetate;benzyl oxo(phenyl)acetate;benzyl-α-oxophenyl acetate;phenylglyoxylic acid benzyl ester
• CAS NO: 62977-82-6
• Molecular Formula: C15H12O3
• Molecular Weight: 240.258
• Mol File: 62977-82-6.mol
• Article Data: 49

Chemical Properties

• Boiling Point: 372.7±21.0 °C(Predicted)
• Density: 1.191±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzeneacetic acid, a-oxo-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, a-oxo-, phenylmethyl ester(62977-82-6)
• EPA Substance Registry System: Benzeneacetic acid, a-oxo-, phenylmethyl ester(62977-82-6)

Safety Data

• Hazardous Substances Data: 62977-82-6(Hazardous Substances Data)

Upstream product

• 25726-04-9 phenylglyoxylyl chloride 
• 85166-50-3 N-Nitroso-N-benzylhydroxylamine Sodium Salt 
• 102-16-9 benzyl 2-phenylacetate 
• 20067-23-6 3-benzyl-4-phenyl-1,2,3-oxadiazol-3-ium-5-olate 
• 501-53-1 benzyl chloroformate 
• 611-73-4 Benzoylformic acid 
• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 100-51-6 benzyl alcohol 
• 5032-98-4 2-triphenylphosphorylidene-3-oxo-3-phenylpropionitrile 
• 62173-99-3 benzyl 2-hydroxy-2-phenylacetate 
• 63468-90-6 phenylglyoxylic acid potassium salt 
• 100-44-7 benzyl chloride 
• 78823-32-2 benzoic formic anhydride 
• 218792-82-6 α-diazo-α-phenylacetic acid benzyl ester 

Downstream Products

• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 111709-17-2 t-butyl 3-(benzyloxycarbonyl)benzylidenecarbazate 
• 62173-99-3 (S)-benzyl 2-hydroxy-2-phenylacetate 
• 1042740-65-7 (S)-benzyl 2-hydroxy-2-(4-methylphenyl)-phenylacetate 
• 1042740-62-4 (R)-benzyl 2-hydroxy-2-(4-methylphenyl)-phenylacetate 
• 1042740-67-9 (S)-benzyl 2-hydroxy-2-(4-methoxyphenyl)-2-phenylacetate 
• 1042740-63-5 (R)-benzyl 2-hydroxy-2-(4-methoxyphenyl)-2-phenylacetate 
• 1034852-82-8 benzyl 2-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)-2-phenylacetate 
• 62173-99-3 benzyl 2-hydroxy-2-phenylacetate 
• 97415-09-3 (R)-benzyl 2-hydroxy-2-phenyl-acetate 
• 93-56-1 phenylethane 1,2-diol 
• 1408233-52-2 N,N,-dihexyl-2-phenylglycine benzyl ester 
• 1408233-66-8 C₁₅H₁₃NO₃ 
• 1408233-67-9 C₂₂H₁₉NO₅S 

Relevant articles and documents

Unraveling two pathways for NHPI-mediated electrocatalytic oxidation reaction

Two pathways for N-hydroxyphthalimide (NHPI)-mediated electrocatalytic oxidation using phenylacetate derivatives as template substrates were first reported for benzylic C[sbnd]H oxidation to oxygenated and non-oxygenated products. DFT calculation indicates that the hydrogen-atom transfer (HAT) process between phthalimido-N-oxyl (PINO) and substrate is a rate-determined step. Aromatic α-keto esters and 2-((1,3-dioxoisoindolin-2-yl)oxy)-2-aryl acetate obtained by cross-coupling between benzylic radical and PINO can be selectively synthesized through controlling the concentration of PINO radical. This method provides a deep understanding for selective weak C[sbnd]H oxidation using NHPI as redox mediator.

Photoinduced Diverse Reactivity of Diazo Compounds with Nitrosoarenes

A diverse reactivity of diazo compounds with nitrosoarene in an oxygen-transfer process and a formal [2 + 2] cycloaddition is reported. Nitosoarene has been exploited as a mild oxygen source to oxidize an in situ generated carbene intermediate under visible-light irradiation. UV-light-mediated in situ generated ketenes react with nitosoarenes to deliver oxazetidine derivatives. These operationally simple processes exemplify a transition-metal-free and catalyst-free protocol to give structurally diverse α-ketoesters or oxazetidines.

Carbene-Catalyzed Enantioselective Aromatic N-Nucleophilic Addition of Heteroarenes to Ketones

The aromatic nitrogen atoms of heteroarylaldehydes are activated by carbene catalysts to react with ketone electrophiles. Multi-functionalized cyclic N,O-acetal products are afforded in good to excellent yields and optical purities. Our reaction involves the formation of an unprecedented aza-fulvene-type acylazolium intermediate. A broad range of N-heteroaromatic aldehydes and electron-deficient ketone substrates works effectively in this transformation. Several of the chiral N,O-acetal products afforded through this protocol exhibit excellent antibacterial activities against Ralstonia solanacearum (Rs) and are valuable in the development of novel agrichemicals for plant protection.