2026-08-6

Basic information

• Product Name: 1,8-BIS(HYDROXYMETHYL)NAPHTHALENE
• Synonyms: 1,8-BIS(HYDRODIMETHYL)NAPHTHALENE;1,8-BIS(HYDROXYMETHYL)NAPHTHALENE;Naphthalene-1,8-bismethanol;Naphthalene-1,8-dimethanol;1,8-Bis(hydroxymethyl)naphthalene,99%;1,8-Naphthalenedimethanol 97%;[8-(Hydroxymethyl)naphthalen-1-yl]methanol;Naphthalene-1,8-diyldimethanol
• CAS NO: 2026-08-6
• Molecular Formula: C₁₂H₁₂O₂
• Molecular Weight: 188.22
• Product Categories: Organic Building Blocks;Oxygen Compounds;Polyols
• Mol File: 2026-08-6.mol
• Article Data: 24

Chemical Properties

• Melting Point: 153-156 °C(lit.)
• Boiling Point: 283.23°C (rough estimate)
• Flash Point: 207.3 °C
• Appearance: /
• Density: 1.0750 (rough estimate)
• Vapor Pressure: 1.7E-07mmHg at 25°C
• Refractive Index: 1.6010 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 14.07±0.10(Predicted)
• CAS DataBase Reference: 1,8-BIS(HYDROXYMETHYL)NAPHTHALENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,8-BIS(HYDROXYMETHYL)NAPHTHALENE(2026-08-6)
• EPA Substance Registry System: 1,8-BIS(HYDROXYMETHYL)NAPHTHALENE(2026-08-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 2026-08-6(Hazardous Substances Data)

Usage

Chemical Properties

WHITE TO ALMOST WHITE FINE CRYSTALLINE POWDER

Uses

1,8-Naphthalenedimethanol may be used in the synthesis of 1,8-bis-(chloromethyl)-naphthalene and 1,8-dimethylnaphthalene.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 34, p. 4335, 1986 DOI: 10.1248/cpb.34.4335

General Description

1,8-Naphthalenedimethanol, also known as 1,8-bis(hydroxymethyl)naphthalene, is an aromatic diol. It can be synthesized by the reduction of 1,8-naphthalic anhydride using lithium aluminum hydride. It crystallizes in the monoclinic space group P21/n.

InChI:InChI=1/C12H12O2/c13-7-10-5-1-3-9-4-2-6-11(8-14)12(9)10/h1-6,13-14H,7-8H2

Upstream product

• 81-84-5 1,8-Naphthalic anhydride 
• 10060-33-0 dimethyl naphthalene-1,8-dicarboxylate 
• 82-86-0 acenaphthene quinone 
• 518-05-8 Naphthalene-1,8-dicarboxylic acid 

Downstream Products

• 203-84-9 1H,3H-benzo[de]isochromene 
• 2025-95-8 1,8-bis(bromomethyl)naphthalene 
• 569-41-5 1,8-dimethylnaphthalene 
• 50585-29-0 1,8-[bis(dichloromethyl)]naphthalene 
• 203-85-0 1H,3H-naphtho<1,8-cd>thiopyran 
• 939026-04-7 (2'-hydroxymethyl-biphenyl-2-yl)diphenylmethanol 
• 24018-02-8 7,7-diphenyl-7H-dibenz[c,e]oxepin-5-one 
• 10336-29-5 1-hydroxymethyl-8-methylnaphthalene 
• 83-32-9 acenaphthene 
• 14209-08-6 1,2-dibromoacenaphthene 
• 214-63-1 Zethren 
• 115029-70-4 3-phenyl-1H,5H-naphtho<1,8-ef><1,3>dithiocin 
• 60948-99-4 1,8-bis(mercaptomethyl)naphthalene 
• 208-96-8 acenaphthylene 

Relevant articles and documents

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Enantiocontrolled macrocycle formation by catalytic intramolecular cyclopropanation

Stereoselectivity in intramolecular cyclopropanation reactions resulting in cyclopropane fusion with ten- and larger-membered rings has been examined using chiral copper(I) and dirhodium(II) catalysts. The influence of alkene structure and catalyst has be

Platinum-on-Carbon-Catalyzed Aqueous Oxidative Lactonization of Diols by Using Molecular Oxygen

A lactonization of various diols catalyzed by platinum on carbon (Pt/C) in water under an atmosphere of molecular oxygen was developed. Derivatives of 1,4- 1,5- and 1,6-diols were transformed into the corresponding five-, six-, and seven-membered lactones by the present oxidative lactonization method.

Intramolecular Parallel [4+3] Cycloadditions of Cyclopropane 1,1-Diesters with [3]Dendralenes: Efficient Construction of [5.3.0]Decane and Corresponding Polycyclic Skeletons

Aiming to develop efficient and general strategies for construction of complex and diverse polycyclic skeletons, we have successfully developed [4+3]IMPC (intramolecular parallel cycloaddition) of cyclopropane 1,1-diesters with [3]dendralenes. With a combination of the [4+3]IMPC and subsequent [4+n] cycloadditions, trans-[5.3.0]decane skeleton and its corresponding structurally complex and diverse polycyclic variants could be constructed efficiently. This novel [4+3] cycloaddition reaction mode of donor–acceptor cyclopropanes proceeds as a result of the ring-strain relief of a trans-[3.3.0]octane. We strongly believe that the developed methods will demonstrate potential applications in natural products synthesis and drug discovery.

Merging Photoredox with Br?nsted Acid Catalysis: The Cross-Dehydrogenative C?O Coupling for sp3 C?H Bond Peroxidation

A photoredox and Br?nsted acid synergistically catalyzed cross-dehydrogenative C?O coupling reaction is developed in which isochroman peroxyacetals are formed through sp3 C?H bond peroxidation. The reported method is characterized by its extremely mild reaction conditions, excellent yields, and broad substrate scope. An oxocarbenium ion p-chlorobenzenesulfonate was speculated to be the reactive intermediate. The role of hemiacetals and oxygenated dimers on the effective stabilization of the oxocarbenium ion was investigated; the presence of acid appeared to establish equilibrium between hemiacetals and oxygenated dimers with the oxocarbenium ion pairs. The broad applicability of the method highlights the potential of the protocol for molecule synthesis.