203-84-9

Basic information

• Product Name: 1H,3H-Naphtho[1,8-cd]pyran
• Synonyms: 1H,3H-Naphtho[1,8-cd]pyran;2,1,3-peri-Naphthopyran
• CAS NO: 203-84-9
• Molecular Formula: C₁₂H₁₀O
• Molecular Weight: 170.21
• Mol File: 203-84-9.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 340.083 °C at 760 mmHg
• Flash Point: 153.937 °C
• Appearance: /
• Density: 1.185 g/cm³
• CAS DataBase Reference: 1H,3H-Naphtho[1,8-cd]pyran(CAS DataBase Reference)
• NIST Chemistry Reference: 1H,3H-Naphtho[1,8-cd]pyran(203-84-9)
• EPA Substance Registry System: 1H,3H-Naphtho[1,8-cd]pyran(203-84-9)

Safety Data

• Hazardous Substances Data: 203-84-9(Hazardous Substances Data)

Usage

Chemical Group

Benzopyrones

Natural Occurrence

Found in plants such as tonka beans, sweet clover, and cassia

Perfumes

Used in the production of perfumes

Flavoring Agent

Used as a flavoring agent in tobacco and food products

Scent

Sweet, vanilla-like

Aroma

Often used to add a pleasant aroma to various products

Regulatory Status

Banned as a food additive in the United States due to potential toxicity at high levels

Anti-Inflammatory

Has anti-inflammatory properties

Anti-Coagulant

Has anti-coagulant properties

Anti-Cancer

Has anti-cancer properties

Pharmaceutical Interest

Subject of interest for pharmaceutical and medicinal applications due to its health benefits.

Upstream product

• 81-84-5 1,8-Naphthalic anhydride 
• 71-43-2 benzene 
• 93131-88-5 1-bromomethyl-8-t-butylperoxymethylnaphthalene 
• 2026-08-6 naphthalene-1,8-diyldimethanol 
• 2025-95-8 1,8-bis(bromomethyl)naphthalene 
• 824-86-2 benzylmethylsulfoxide 
• 182313-41-3 (8-(((tert-butyldimethylsilyl)oxy)methyl)naphthalen-1-yl)methanol 
• 182313-42-4 Propynoic acid 8-(tert-butyl-dimethyl-silanyloxymethyl)-naphthalen-1-ylmethyl ester 

Downstream Products

• 714963-37-8 1-[(1-hydroxycyclohexyl)methyl]-8-hydroxymethylnaphthalene 
• 10336-29-5 1-hydroxymethyl-8-methylnaphthalene 
• 569-41-5 1,8-dimethylnaphthalene 

Relevant articles and documents

Solvent-free synthesis of cyclic ethers from dihalo compounds in the presence of alumina

Facile synthesis of cyclic ethers from dihalo compounds on alumina has been accomplished in good yields. The reactions proceeded smoothly both in refluxing hexane and by microwave irradiation in the absence of solvent. In addition to being an organic-solvent-free operation, it also entails a short reaction time.

HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF

Provided herein are heterocyclyl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders, including but not limited to, psychosis and schizophrenia.

HYDROXY ALKYL SUBSTITUTED 1,3,8-TRIAZASPIRO[4.5]DECAN-4-ONE DERIVATIVES USEFUL FOR THE TREATMENT OF ORL-1 RECEPTOR MEDIATED DISORDERS

The present invention is directed to novel hydroxy alkyl substituted 1, 3, 8-triazaspiro[4.5]decan-4-one derivatives of the general formula: wherein all variables are as defined herein, useful in the treatment of disorders and conditions mediated by the ORL-1 G-protein coupled receptor. More particularly, the compounds of the present invention are useful in the treatment of disorders and conditions such as anxiety, depression, panic, dementia, mania, bipolar disorder, substance abuse, neuropathic pain, acute pain, chronic pain migraine, asthma, cough, psychosis, schizophrenia, epilepsy, hypertension, obesity, eating disorders, cravings, diabetes, cardiac arrhythmia, irritable bowel syndrome, Crohn's disease, urinary incontinence, adrenal disorders, attention deficit disorder (ADD), attention deficit hyperactivity disorder (ADHD), Alzheimer's disease, for improved cognition or memory and for mood stabilization.