2026-11-1

Upstream product

• 1100-88-5 benzyltriphenylphosphonium chloride 
• 541-41-3 chloroformic acid ethyl ester 
• 2882-19-1 ethyl 2-phenyl-2-bromoacetate 
• 603-35-0 triphenylphosphine 
• 78489-65-3 ethyl α-iodophenylacetate 
• 101-97-3 Ethyl 2-phenylethanoate 

Downstream Products

• 41309-41-5 C₁₆H₁₄N₄O₄ 
• 17437-51-3 N-(ethoxycarbonyl)triphenylphosphinimine 
• 14987-96-3 N-(4-bromophenyl)triphenyliminophosphorane 
• 17437-54-6 N-(p-nitrobenzoyl)triphenylphospha-λ⁵-azene 
• 25957-17-9 3-phenyl-2H-pyrano<3,2-b>pyridin-2-one 
• 113246-38-1 1,3,4-Triphenyl-5-ethoxypyrazole 
• 36858-84-1 ethyl 2,4,4-triphenyl-2,3-butadienoate 
• 107933-78-8 4,6-dimethoxy-2-phenylbenzo[b]furan 
• 171511-98-1 Cyclopropylidene-phenyl-acetic acid ethyl ester 
• 380375-72-4 7-methoxy-6-prenyl-3-phenylcoumarin 

Relevant academic research and scientific papers

Metal-Free Transfer Hydroiodination of C-C Multiple Bonds

The design and a gram-scale synthesis of a bench-stable cyclohexa-1,4-diene-based surrogate of gaseous hydrogen iodide are described. By initiation with a moderately strong Br?nsted acid, hydrogen iodide is transferred from the surrogate onto C-C multiple bonds such as alkynes and allenes without the involvement of free hydrogen iodide. The surrogate fragments into toluene and ethylene, easy-to-remove volatile waste. This hydroiodination reaction avoids precarious handling of hydrogen iodide or hydroiodic acid. By this, a broad range of previously unknown or difficult-to-prepare vinyl iodides can be accessed in stereocontrolled fashion.

Construction of Pyrrolo[1,2-a]indoles via Cobalt(III)-Catalyzed Enaminylation of 1-(Pyrimidin-2-yl)-1H-indoles with Ketenimines and Subsequent Base-Promoted Cyclization

A cobalt(III)-catalyzed cross-coupling reaction of 1-(pyrimidin-2-yl)-1H-indoles with ketenimines is reported. The reaction provided 2-enaminylated indole derivatives in moderate to excellent yields with a broad substrate scope. The prepared 2-enaminylated indoles could be conveniently converted into pyrrolo[1,2-a]indoles, which are an important class of compounds in medicinal chemistry.