20271-33-4

Basic information

• Product Name: ETHYL 5-AMINO-1-BENZYL-1H-1,2,3-TRIAZOLE-4-CARBOXYLATE
• Synonyms: ETHYL 5-AMINO-1-BENZYL-1H-1,2,3-TRIAZOLE-4-CARBOXYLATE;1H-1,2,3-Triazole-4-carboxylic acid, 5-aMino-1-(phenylMethyl)-, ethyl ester;5-amino-1-(benzyl)triazole-4-carboxylic acid ethyl ester;5-amino-1-(phenylmethyl)-4-triazolecarboxylic acid ethyl ester;ethyl 5-amino-1-(phenylmethyl)-1,2,3-triazole-4-carboxylate;ethyl 5-amino-1-(phenylmethyl)triazole-4-carboxylate
• CAS NO: 20271-33-4
• Molecular Formula: C₁₂H₁₄N₄O₂
• Molecular Weight: 246.27
• Mol File: 20271-33-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 444.5°C at 760 mmHg
• Flash Point: 222.6°C
• Appearance: /
• Density: 1.3g/cm³
• Vapor Pressure: 4.27E-08mmHg at 25°C
• Refractive Index: 1.625
• PKA: -0.26±0.17(Predicted)
• CAS DataBase Reference: ETHYL 5-AMINO-1-BENZYL-1H-1,2,3-TRIAZOLE-4-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 5-AMINO-1-BENZYL-1H-1,2,3-TRIAZOLE-4-CARBOXYLATE(20271-33-4)
• EPA Substance Registry System: ETHYL 5-AMINO-1-BENZYL-1H-1,2,3-TRIAZOLE-4-CARBOXYLATE(20271-33-4)

Safety Data

• Hazardous Substances Data: 20271-33-4(Hazardous Substances Data)

Usage

General Description

ETHYL 5-AMINO-1-BENZYL-1H-1,2,3-TRIAZOLE-4-CARBOXYLATE is a chemical compound with the molecular formula C14H14N4O2. It is a derivative of 1,2,3-triazole and contains an amino group, a benzyl group, and a carboxylic acid ester group. ETHYL 5-AMINO-1-BENZYL-1H-1,2,3-TRIAZOLE-4-CARBOXYLATE is commonly used in organic synthesis and medicinal chemistry as a building block for the synthesis of various pharmaceutical drugs and biologically active molecules. It has potential applications in the development of new drugs for the treatment of various diseases and medical conditions. As a chemical, it is important to handle and use ETHYL 5-AMINO-1-BENZYL-1H-1,2,3-TRIAZOLE-4-CARBOXYLATE with care and caution due to its potential hazards and reactivity.

InChI:InChI=1/C12H14N4O2/c1-2-18-12(17)10-11(13)16(15-14-10)8-9-6-4-3-5-7-9/h3-7H,2,8,13H2,1H3

Upstream product

• 105-56-6 ethyl 2-cyanoacetate 
• 622-79-7 benzyl azide 
• 100-39-0 benzyl bromide 
• 64-17-5 ethanol 
• 141-52-6 sodium ethanolate 

Downstream Products

• 4342-08-9 4-amino-3-benzyl-1,2,3-triazole-5-carboxamide 
• 16975-91-0 5-Amino-1-benzyl-1,2,3-triazole-4-carboxylic Acid Hydrazide 
• 127572-34-3 3-Benzyl-6-[2-(3,4-dimethoxy-phenyl)-ethyl]-3,6-dihydro-[1,2,3]triazolo[4,5-d]pyrimidin-7-one 
• 104699-70-9 5-Amino-1-benzyl-4,5-dihydro-1,2,3-triazolo<4,5-d>pyrimidin-4-one 
• 94018-11-8 N,5,6-trimethyl-3-phenylmethyl-3H-1,2,3-triazolo<4,5-d>pyrimidin-7(6)H-imine 
• 94018-47-0 6-ethyl-5-methyl-3-phenylmethyl-3H-1,2,3-triazolo<4,5-d>pyrimidin-7(6)H-one 
• 94018-12-9 N,6-diethyl-5-methyl-3-phenylmethyl-3H-1,2,3-triazolo<4,5-d>pyrimidin-7(6)H-imine 
• 94018-46-9 5,6-dimethyl-3-phenylmethyl-3H-1,2,3-triazolo<4,5-d>pyrimidin-7(6)H-one 
• 112881-66-0 3,7-dihydro-3-benzyl-7-methyl-5-phenyl-9H-bis<1,2,3>triazolo<1,5-a:4',5'-d>pyrimidin-9-one 
• 112881-62-6 3,4-dihydro-3-benzyl-5-phenyl-9H-bis<1,2,3>triazolo<1,5-a:4',5'-d>pyrimidin-9-one 
• 112881-63-7 3,4-dihydro-3-benzyl-5-cyano-9H-bis<1,2,3>triazolo<1,5-a:4',5'-d>pyrimidin-9-one 
• 36540-27-9 1-benzyl-4,5-diamino-1,2,3-triazole 
• 103742-40-1 1-benzyl-5-amino-1,2,3-triazole-4-carbamic acid methyl ester 
• 36540-25-7 1-benzyl-5-amino-1,2,3-triazole-4-carbonyl azide 

Relevant articles and documents

Ruthenium-catalyzed synthesis of 5-amino-1,2,3-triazole-4-carboxylates for triazole-based scaffolds: Beyond the Dimroth rearrangement

The 5-amino-1,2,3-triazole-4-carboxylic acid is a suitable molecule for the preparation of collections of peptidomimetics or biologically active compounds based on the triazole scaffold. However, its chemistry may be influenced by the possibility of under

A MODIFIED SCHEME FOR THE SYNTHESIS OF 1-BENZYL-4,5-DIAMINO-1,2,3-TRIAZOLE

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