20279-38-3 Usage
Description
Succinic Acid Monoisopropyl Ester, also known as Monoisopropyl Succinate, is an organic compound derived from succinic acid and isopropanol. It is a colorless liquid with a mild odor and is soluble in water and most organic solvents. Its chemical structure consists of a four-carbon dicarboxylic acid with an isopropyl ester group attached to one of the carboxylic acid groups. This unique structure endows it with versatile properties, making it a valuable intermediate in the synthesis of various chemicals and pharmaceuticals.
Uses
Used in Pharmaceutical Industry:
Succinic Acid Monoisopropyl Ester is used as an intermediate in the synthesis of prodrugs for the treatment or prevention of central nervous system (CNS) diseases. One such application is in the preparation of prodrugs of ketamine, a dissociative anesthetic and analgesic drug. The esterification of ketamine with Succinic Acid Monoisopropyl Ester enhances its solubility, bioavailability, and pharmacokinetic properties, allowing for more effective treatment of CNS disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 20279-38-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,2,7 and 9 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 20279-38:
(7*2)+(6*0)+(5*2)+(4*7)+(3*9)+(2*3)+(1*8)=93
93 % 10 = 3
So 20279-38-3 is a valid CAS Registry Number.
20279-38-3Relevant articles and documents
Direct oxidative cleavage of α- and β-dicarbonyls and α-hydroxyketones to diesters with KHSO5
Yan, Jun,Travis, Benjamin R.,Borhan, Babak
, p. 9299 - 9302 (2007/10/03)
Presented is a methodology to oxidatively cleave α-hydroxyketones and α- or β-diones using the environmentally benign reagent KHSO 5, prepared easily from Oxone, to diesters in one simple transformation. In addition, we undertook a mechanistic study to provide a plausible mechanistic interpretation. These reactions may prove to be valuable alternatives to other related metal-mediated processes.