202832-49-3Relevant academic research and scientific papers
A new method for the selective amination of 1,3- and 1,4-dinitrobenzenes and protected nitroanilines leading to polyfunctional 1,3- and 1,4-disubstituted anilines
Sapountzis, Ioannis,Knochel, Paul
, p. 955 - 958 (2004)
The addition of functionalized arylmagnesium reagents to dinitrobenzenes and protected nitroanilines at -20°C in THF furnishes after a reductive workup polyfunctional diarylamines in 47-92% yield.
COMPOUNDS AND METHODS FOR TREATING PROTEIN FOLDING DISORDERS
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Page/Page column 130, (2008/12/05)
The invention is directed to compounds and methods for treating protein folder disorders. In certain embodiments the invention provides compounds and methods for treating neurodegenerative diseases such as Alzheimer's disease, tauopathy, cerebral amyloid angiopathy, Lewy body disease, dementia, Huntington's disease and prion-based spongiform encelopathy. The invention further provides compounds, methods and pharmaceutical compositions for inhibiting tau protein, Aβ protein or α-synuclein protein aggregation.
Palladium-catalyzed synthesis of pure, regiodefined polymeric triarylamines
Goodson, Felix E.,Hauck, Sheila I.,Hartwig, John F.
, p. 7527 - 7539 (2007/10/03)
Triarylamine polymers were prepared by palladium-catalyzed amination of aryl halides, and the electrochemical and magnetic properties of these materials were studied. Through a careful evaluation of the catalytic and polymer chemistry involved in this pro
Preparation and characterization of novel DPPH-based diradicals
Kozaki, Masatoshi,Nakamura, Shogo,Sato, Kazunobu,Takui, Takeji,Kamatani, Takeaki,Oda, Masaji,Tokumaru, Katsumi,Okada, Keiji
, p. 5979 - 5982 (2007/10/03)
A series of 1,1'(2,4-di-X-benzene-1,3-diyl)bis[1-(4-Y-phenyl)-2- picrylhydrazine]s were prepared an oxidized to generate the corresponding bis-DPPH diradicals. No triplet species was observed for the compounds with X = H in the ESR measurement. Modification of the central benzene ring (x = Me) and N-phenyl group (Y = OMe, P, t-Bu) allowed the detection of their triplet diradicals. Especially, the diradical with X = Me, Y = t-Bu was successfully purified, isolated at O aC as a purple solid, and was shown to be in a triplet ground state.
