699-19-4

Basic information

• Product Name: Magnesium, chloro(4-methoxyphenyl)-
• CAS NO: 699-19-4
• Molecular Formula: C7H7ClMgO
• Molecular Weight: 166.89
• Mol File: 699-19-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Magnesium, chloro(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Magnesium, chloro(4-methoxyphenyl)-(699-19-4)
• EPA Substance Registry System: Magnesium, chloro(4-methoxyphenyl)-(699-19-4)

Safety Data

• Hazardous Substances Data: 699-19-4(Hazardous Substances Data)

Upstream product

• 623-12-1 4-chloromethoxybenzene 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 696-62-8 para-iodoanisole 

Downstream Products

• 88849-27-8 4-methoxy-N-(3-nitrophenyl)benzenamine 
• 202832-49-3 N,N'-bis(4-methoxyphenyl)-1,3-phenylenediamine 
• 730-11-0 4-methoxy-N-(4-nitrophenyl)aniline 
• 100-09-4 4-methoxybenzoic acid 
• 1059091-54-1 C₁₉H₁₇OPSe₂ 
• 66472-51-3 1-(1-fluorovinyl)-4-methoxybenzene 
• 100-66-3 methoxybenzene 
• 1079330-52-1 (E)-2-ethyl-1-(4-methoxyphenyl)-1-hexene 
• 1657-53-0 cis-4-methoxystilbene 
• 1694-19-5 E-1-(phenyl)-2-(4'-methoxyphenyl)ethene 
• 54395-67-4 2-(p-methoxybenzyl)-1,4,5-trimethyl-2,3,3,6-tetrahydropyridine 
• 54395-66-3 2-(p-methoxybenzyl)-1,3,4-trimethyl-2,3,3,6-tetrahydropyridine 
• 502607-25-2 3,3,3-trifluoro-2-hydroxy-2-(4-methoxyphenyl)propanoic acid 
• 711-38-6 4'-methoxy-2,2,2-trifluoroacetophenone 

Relevant articles and documents

Regioselective 1,4-conjugate addition of grignard reagents to nitrodienes in the presence of catalytic amounts of Zn(II) salts

Grignard reagents undergo facile regioselective 1,4-conjugate addition to nitrodienes in the presence of catalytic amounts of Zn(II) salts with excellent yields. A wide range of ligands such as alkyl, aryl, heteroaryl, allyl, vinyl, 1-alkynyl, and alkoxy ligands were transferred, while a thiolate ligand afforded 1,6-regioselectivity. The reactions were successfully carried out on δ-alkyl- or aryl-substituted α,β,γ,δ-diunsaturated nitrodiene substrates. Regioselectivity is minimally influenced by temperature or choice of solvent.

Arylzinc species by microwave assisted Grignard formation-transmetallation sequence: Application in the Negishi coupling

Arylmagnesium species can be efficiently generated from magnesium turnings and aryl chlorides or aryl bromides under dielectric heating conditions. Subsequent microwave assisted transmetallation using ZnCl2-TMEDA afforded the corresponding arylzinc reagents. A sequential microwave assisted arylmagnesium formation-transmetallation-Negishi coupling protocol suitable for automated multiple parallel synthesis has been developed.