203056-20-6 Usage
Molecular weight
346.24 g/mol
Structure
The molecule consists of a piperidine ring (a six-membered nitrogen-containing ring) with a carboxylic acid group (-COOH) attached to the 1-position and a 4-bromo-benzoyl group (a benzoyl group with a bromine atom attached to the 4-position) attached to the 2-position. The carboxylic acid group is further esterified with a tert-butyl group (a -C(CH\3)\3 group).
Reactivity
The presence of the bromo-benzoyl group confers specific reactivity to the compound, making it useful in the formation of new carbon-carbon and carbon-heteroatom bonds.
Protection
The tert-butyl ester group provides protection for the carboxylic acid moiety and can be cleaved under appropriate conditions to reveal the free carboxylic acid functionality.
Use
2-(4-bromo-benzoyl)-piperidine-1-carboxylic acid tert-butyl ester is a versatile intermediate for the preparation of biologically active molecules and is used in the synthesis of various pharmaceuticals and agrochemicals.
Derivative
It is a derivative of piperidine, which is commonly used as a building block in organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 203056-20-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,3,0,5 and 6 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 203056-20:
(8*2)+(7*0)+(6*3)+(5*0)+(4*5)+(3*6)+(2*2)+(1*0)=76
76 % 10 = 6
So 203056-20-6 is a valid CAS Registry Number.
203056-20-6Relevant articles and documents
Asymmetric synthesis and pharmacology of methylphenidate and its para- substituted derivatives
Thai, Dung L.,Sapko, Michael T.,Reiter, Clara T.,Bierer, Donald E.,Perel, James M.
, p. 591 - 601 (2007/10/03)
We report the first asymmetric synthesis of the individual enantiomers of methylphenidate (1). From d-pipecolic acid, the (2R,2'R) and (2S,2'R) enantiomers of 1 were obtained in >99% optical purity while the (2S,2'S) and (2R,2'S) enantiomers of 1 were der
