203065-98-9Relevant academic research and scientific papers
Highly efficient and enantioselective synthesis of L-arylglycines and D-arylglycine amides from biotransformations of nitriles
Wang, Mei-Xiang,Lin, Shuang-Jun
, p. 6925 - 6927 (2001)
Under very mild conditions, the Rhodococcus sp. AJ270-catalysed biotransformation of arylglycine nitriles 1, prepared easily from the reaction of substituted benzaldehydes, ammonium chloride and potassium cyanide, proceeded efficiently to produce optically active D-arylglycine amides 2 and L-arylglycines 3 in excellent yields with enantiomeric excesses higher than 99%.
2-ARYL GLYCINAMIDE DERIVATIVES
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Page/Page column 36-37, (2010/01/29)
The disclosure provides compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their uses in inhibiting β-amyloid peptide ( β-AP) production.
