20313-41-1Relevant academic research and scientific papers
Designed synthesis of new ortho-carborane derivatives: From mono- to polysubstituted frameworks
Barbera, Gemma,Vaca, Albert,Teixidor, Francesc,Sillanpaeae, Reijo,Kivekaes, Raikko,Vinas, Clara
, p. 7309 - 7316 (2009/02/06)
The use of nucleophilic and electrophilic processes allow the designed synthesis of several B-iodinated derivatives of o-carborane. Because of the straightforward Pd-catalyzed conversion of B-I to B-C bond with Grignard reagents, such as methylMgBr and biPhenylMgBr, both, symmetrical 3,6-R 2-1,2-closo-C2B10H10 and asymmetrical 3-I-6-Me-1,2-closo-C2B10H10 could be obtained. Not only conventional reactions in solution have been studied but also a highly efficient, clean and fast solvent-free procedure has provided successful results to regioselectively produce B-iodinated o-carborane derivatives by a careful control of the reaction conditions. The high number of nonequivalent leaving groups in boron iodinated o-carborane derivatives opens the possibility through B-C coupling to materials with novel possibilities and to self-assembling due to the enhanced polarizability of the C-H bond.
