20321-45-3Relevant academic research and scientific papers
Metal-Free C-O Bond Functionalization: Catalytic Intramolecular and Intermolecular Benzylation of Arenes
Bering, Luis,Jeyakumar, Kirujan,Antonchick, Andrey P.
supporting information, p. 3911 - 3914 (2018/07/22)
A catalytic, metal-free intramolecular rearrangement of benzyl phenyl ethers using nitrosonium salt as a catalyst is described. The optimized reaction conditions enabled a catalytic and metal-free Friedel-Crafts alkylation reaction with benzylic alcohols, producing water as the stoichiometric byproduct. A comprehensive scope (>50 examples) for both approaches and application in drug synthesis were demonstrated. Mechanistic studies suggest a Lewis acid-based mechanism for the metal-free Friedel-Crafts reaction.
The selective hydrogenolysis of C-O bonds in lignin model compounds by Pd-Ni bimetallic nanoparticles in ionic liquids
Sun, Kang-Kang,Lu, Guo-Ping,Zhang, Jia-Wei,Cai, Chun
, p. 11884 - 11889 (2017/09/18)
β-O-4 and α-O-4 linkages can be selectively cleaved by Pd-Ni bimetallic nanoparticles in ionic liquids using hydrogen gas as the hydrogen donor under ambient pressure and neutral conditions. No hydrogenation of the benzene ring takes place in the catalytic system. An obvious improvement in activity is found compared with single nickel and palladium catalysts based on the results of experiments and characterization. After the reaction, the catalytic system still remains in the reactor by simple extraction, which can be reused without further treatment.
