20324-50-9

Basic information

• Product Name: 5-CHLORO-2-MERCAPTOBENZOIC ACID
• Synonyms: 5-CHLORO-2-MERCAPTOBENZOIC ACID;Benzoic acid, 5-chloro-2-Mercapto-
• CAS NO: 20324-50-9
• Molecular Formula: C₇H₅ClO₂S
• Molecular Weight: 188.63
• Mol File: 20324-50-9.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-CHLORO-2-MERCAPTOBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CHLORO-2-MERCAPTOBENZOIC ACID(20324-50-9)
• EPA Substance Registry System: 5-CHLORO-2-MERCAPTOBENZOIC ACID(20324-50-9)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 20324-50-9(Hazardous Substances Data)

Usage

General Description

5-CHLORO-2-MERCAPTOBENZOIC ACID is a chemical compound with the molecular formula C7H5ClO2S. It is a chlorinated derivative of benzoic acid with a thiol functional group. 5-CHLORO-2-MERCAPTOBENZOIC ACID is commonly used in the synthesis of pharmaceuticals and agrochemicals. It has also been studied for its potential antioxidant and antimicrobial properties. Additionally, 5-CHLORO-2-MERCAPTOBENZOIC ACID has been used in research to study the effects of oxidative stress and inflammation. Overall, this compound has a range of potential applications in various fields due to its unique chemical structure and properties.

Upstream product

• 140-89-6 potassium ethyl xanthogenate 
• 57381-34-7 5-chloro-2-fluorobenzonitrile 
• 38244-31-4 5-chloro-2-mercaptobenzonitrile 
• 88279-11-2 2-carboxy-4-chlorophenyl azide 
• 4068-78-4 methyl 5-chloro-2-hydroxybenzoate 
• 635-21-2 5-chloroanthranilic acid 
• 69135-70-2 2,2'-dithiobis<5-chlorobenzoic acid> 

Downstream Products

• 89756-74-1 5-chloro-2-<<5-(2,4-dichlorophenyl)-3-oxo-1-cyclohexen-1-yl>thio>benzoic acid 
• 120121-37-1 4-chloro-2-(hydroxymethyl)thiophenol 
• 25697-88-5 2-(benzylthio)-5-chlorobenzoic acid 
• 66949-65-3 2-(4-Acetylphenylthio)-5-chlorbenzoesaeure 
• 198897-07-3 5-Chloro-2-(2-methylcarbamoyl-phenylsulfanyl)-benzoic acid 
• 4700-07-6 5-chloro-2-mercaptobenzophenone 
• 1020412-76-3 5-chloro-2-(4-ethoxycarbonyl-2-nitrophenylthio)benzoic acid 
• 712302-46-0 2-(benzhydrylthio)benzoic acid 
• 74053-24-0 6,6'-thiobis(3-chlorobenzoic acid) 
• 25700-47-4 5-Chloro-2-(3-trifluoromethyl-phenylmethanesulfonyl)-benzoic acid 
• 25700-49-6 2-4'-chlorobenzylsulfonyl-5-chlorobenzoic acid 
• 25700-46-3 5-Chloro-2-phenylmethanesulfonyl-benzoic acid 
• 40183-36-6 2'-(Benzylthio)-5'-chloracetophenon 

Relevant articles and documents

Chemical synthesis, crystal structure, versatile evaluation of their biological activities and molecular simulations of novel pyrithiobac derivatives

Since pyrithiobac (PTB) is a successful commercial herbicide with very low toxicity against mammals, it is worth exploring its derivatives for an extensive study. Herein, a total of 35 novel compounds were chemically synthesized and single crystal of 6–6

HETEROCYCLIC DERIVATIVE HAVING INHIBITORY ACTIVITY ON TYPE-I 11 -HYDROXYSTEROID DEHYDROGENASE

Disclosed is a compound which is useful as an 11β-hydroxysteroid dehydrogenase type 1 inhibitor. A compound represented by the formula: its pharmaceutically acceptable salt, or a solvate thereof, wherein X is O or S, a broken line and a wavy line represent the presence or the absence of a bond, (i) when a broken line represents the presence of a bond, a wavy line represents the absence of a bond, R2 and R3 are each independently hydrogen, halogen, cyano, hydroxy, carboxy, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl or the like, (ii) when a broken line represents the absence of a bond, a wavy line represents the presence of a bond, R1 and R4 are each independently hydrogen, halogen or the like, R2 and R3 are each independently hydrogen, halogen, cyano, hydroxy, carboxy, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl or the like, and R5 and R6 are each independently hydrogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl or the like.

Substituent effects on the reactivity of benzo-1,2-dithiolan-3-one 1-oxides and their possible application to the synthesis of DNA-targeting drugs

The efficiency of polysulfane product generation has been investigated for n-propyl thiol reactions with ortho- and para-substituted benzo-1,2-dithiolan-3- one 1-oxides in acetonitrile-water (7:3) mixtures. The reaction is facilitated by reducing the electron density at the para position or by placing substituents bearing lone pair electrons ortho to the dithiolanone-oxide (S1) reaction center. Through-space and through-bond effects both contribute to the conversion of polysulfane products.