203259-52-3 Usage
General Description
6-Chloro-benzo[d]isoxazole-3-carboxylic acid ethyl ester is a chemical compound with the molecular formula C11H8ClNO3. It is an ester derivative of benzo[d]isoxazole-3-carboxylic acid, which is a heterocyclic compound with potential pharmaceutical applications. The ethyl ester form of this compound is often used in organic synthesis and drug development due to its reactivity and ability to be easily manipulated. This chemical is also used as a building block in the synthesis of various biologically active molecules and pharmaceuticals. Additionally, it is important to handle this chemical with care and ensure proper storage and disposal to prevent any potential hazards to human health and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 203259-52-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,3,2,5 and 9 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 203259-52:
(8*2)+(7*0)+(6*3)+(5*2)+(4*5)+(3*9)+(2*5)+(1*2)=103
103 % 10 = 3
So 203259-52-3 is a valid CAS Registry Number.
203259-52-3Relevant articles and documents
Studies on agents with vasodilator and β-blocking activities. V. Synthesis and pharmacological activity of the optical isomers of TZC-5665
Seki, Toshimi,Kanada, Arihiro,Nakao, Tomio,Shiraiwa, Masahumi,Asano, Hajime,Miyazawa, Katuhiko,Ishimori, Tsutomu,Minami, Nobuyoshi,Shibata, Kenyu,Yasuda, Kikuo
, p. 84 - 96 (2007/10/03)
Synthesis of the four optical isomers of TZC-5665 (1), a candidate for the treatment of congestive heart failure, was achieved by the reaction of chiral diaminopyridazinone (2) with chiral glycidyl ether (3). The hypotensive and β-blocking activities of 1 and its optical isomers were examined when given intravenously into anesthetized rats. Furthermore these compounds were evaluated for inhibitory activity on cAMP phosphodiesterase III. Among the four optical isomers, R(A),S(B)-one (1c) possessed the essential activities of TZC-5665 (1).
