20332-96-1

Upstream product

• 74394-96-0 3-phenyl-2-propenyl thiocyanate 
• 30953-25-4 2-phenylbut-3-enoic acid 
• 104-54-1 3-Phenylpropenol 
• 4393-21-9 1-(phenyl)allylamine 
• 103205-11-4 Vinyl-phenyl-acetamid 
• 100-52-7 benzaldehyde 
• 6258-61-3 3-phenylprop-2-ene-1-thiol 
• 102860-02-6 1,3-Dicyclohexyl-2-((E)-3-phenyl-allyl)-isourea 
• 41946-78-5 S-cinnamyl S-methyl dithiocarbonate 
• 2687-12-9 cinnamyl chloride 

Relevant academic research and scientific papers

An efficient metal-free synthesis of organic disulfides from thiocyanates using poly-ionic resin hydroxide in aqueous medium

An efficient and metal-free method is described for the preparation of organic disulfides from alkyl and acyl methyl thiocyanates in the presence of poly-ionic resin hydroxide in aqueous medium. Further extension of this protocol has been tested using two different organyl thiocyanates to prepare unsymmetrical disulfides.

Bis[3-(4′-substituted phenyl)prop-2-ene]disulfides as a new class of antihyperlipidemic compounds

Novel derivatives of diallylsulfide, an active principle found in garlic, have been synthesized. The synthetic scheme, involving the Wittig reaction has been outlined. Among these derivatives, bis[3-(4′-nitrophenyl)prop-2-ene] disulfide has been found to be effective in lowering lipid levels and in inhibiting the activity of the enzyme HMG-CoA reductase, in Wistar rats. A series of bis[3-(4′-substituted phenyl)prop-2-ene]disulfides were prepared and their hypolipidemic activities were examined in hypercholesterolemic Wistar rats. Introduction of an electron withdrawing group to the phenyl ring in the parent compound led to the identification of compound 8 as a potent and efficacious hypolipidemic agent.

DIALLYLDISULPHIDE COMPOUNDS HAVING ANTILIPIDEMIC AND ANTIOXIDANT ACTIVITY

The present invention relates to a novel diallyldisulphide derivative having formula I as shown herebelow and their pharmaceutically acceptable salts; R-CH = CH - CH2-S-S-CH2-CH = CH-R (Formula I)wherein R=C6HnX

One pot conversion of alcohols to disulfides mediated by benzyltriethylammonium tetrathiomolybdate

A one pot conversion of alcohols to disulfides in good yields via the activation of a hydroxyl group with DCC or P(NMe2)3 / CCl4 followed by treatment with benzyltriethylammonium tetrathiomolybdate is reported.