203387-34-2

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 93454-85-4 (S)-3-(tert-butyldimethylsilyloxy)-2-methylpropionic acid methyl ester 
• 112057-64-4 (R)-3-(tert-butyldimethylsilyloxy)-2-methylpropan-1-ol 
• 449174-20-3 methyl (R)-N-methyl-N-methoxy-3-(4-methoxybenzyloxy)-2-methylpropanoate 
• 203387-40-0 dimethyl (3R)-3-methyl-4-(p-methoxybenzyloxy)-2-oxobutane-1-phosphonate 
• 212051-35-9 (R)-methyl 3-((4-methoxybenzyl)oxy)-2-methylpropanoate 
• 143619-05-0 (2R)-1-(tert-butyl(dimethyl)silyloxy)-4,4-dibromo-2-methylbut-3-ene 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 203387-42-2 (2R,3S,6R)-7-(tert-butyl(dimethyl)silyloxy)-1-(p-methoxybenzyloxy)-2,6-dimethyl-hept-4-en-3-ol 
• 203387-41-1 (2R,6R)-7-(tert-butyl(dimethyl)silyloxy)-1-(p-methoxybenzyloxy)-2,6-dimethyl-hept-4-en-3-one 
• 203387-43-3 tert-Butyl-{(R)-4-[(4S,5R)-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-2-methyl-butoxy}-dimethyl-silane 
• 104701-87-3 (2S)-3-(tert-butyl-dimethyl-silyloxy)-2-methyl-propanal 
• 668461-34-5 (3R,4S,7R)-8-(tert-butyl(dimethyl)silyloxy)-4-(p-methoxybenzyloxy)-3,7-dimethyl-2-octanol 
• 668461-03-8 (2R,6R)-7-(tert-butyl(dimethyl)silyloxy)-1-(p-methoxybenzyloxy)-2,6-dimethylhept-4-yn-3-one 

Downstream Products

• 203387-45-5 (12E,14Z)-(2R,5S,6S,9S,18S)-1-(tert-Butyl-dimethyl-silanyloxy)-18-(tert-butyl-diphenyl-silanyloxy)-9-hydroxy-5-(4-methoxy-benzyloxy)-2,6-dimethyl-nonadeca-12,14-dien-7-one 
• 203387-54-6 (2R,5S,6S,9S,12E,14Z,18S)-18-(tert-butyl(diphenyl)silyloxy)-2,6-dimethyl-5,9-di-(p-methoxybenzyloxy)-7-oxo-nonadeca-12,14-dienal 
• 668461-37-8 (2R,5S,6S,9S,12E,14Z,18S)-18-(tert-butyl(diphenyl)silyloxy)-2,6-dimethyl-5,9-di-(p-methoxybenzyloxy)-1-hydroxynonadeca-12,14-dien-7-one 
• 668461-36-7 (2R,5S,6S,9S,12E,14Z,18S)-1-(tert-butyl(dimethyl)silyloxy)-18-(tert-butyl(diphenyl)silyloxy)-2,6-dimethyl-5,9-di-(p-methoxybenzyloxy)-nonadeca-12,14-dien-7-one 
• 668461-38-9 methyl (4R,7S,8S,11S,14E,16Z,20S)-20-(tert-butyl(diphenyl)silyloxy)-4,8-dimethyl-9-oxo-2,7,11-tri-(p-methoxybenzyloxy)-unicosa-14,16-dienoate 
• 203387-32-0 methyl (4R,7S,8S,11S,14E,16Z,20S)-20-(tert-butyl(diphenyl)silyloxy)-4,8-dimethyl-3,9-dioxo-2,7,11-tri-(p-methoxybenzyloxy)-unicosa-14,16-dienoate 

Relevant academic research and scientific papers

Horner-Wadsworth-Emmons reactions as a facile entry to biogenetic key substructures

One-pot Horner-Wadsworth-Emmons reactions are used to synthesize α,β-enones with two configurationally independent stereogenic centers. These intermediates are used for the construction of polyketide and monosaccaride fragments. In particular, novel approaches to the branched pentoses mycarose and arcanose are described.

Total Synthesis of the Boron-Containing Ion Carrier Antibiotic Macrodiolide Tartrolon B

The first total synthesis of the boron-containing macrodiolide antibiotic tartrolon B is reported in full detail. Two convergent approaches to the target compound are described, the first of which eventually failed, due to sensitive functionality. In the

Studies directed towards the total synthesis of the antibiotic macrodiolide tartrolon: EPC synthesis of the protected seco acid

An efficient synthesis of the protected seco acid 2 of the antibiotic macrodiolide tartrolon 1 is described. Key steps are a substrate controlled aldol-reaction, a Johnson-Claisen rearrangement, and a Horner-Wadsworth-Emmons olefination with subsequent Co