203387-43-3

Upstream product

• 203387-52-4 (2R,3S,6R)-7-(tert-butyl(dimethyl)silyloxy)-1-(p-methoxybenzyloxy)-2,6-dimethylheptan-3-ol 
• 104701-87-3 (2S)-3-(tert-butyl-dimethyl-silyloxy)-2-methyl-propanal 
• 203387-41-1 (2R,6R)-7-(tert-butyl(dimethyl)silyloxy)-1-(p-methoxybenzyloxy)-2,6-dimethyl-hept-4-en-3-one 
• 203387-42-2 (2R,3S,6R)-7-(tert-butyl(dimethyl)silyloxy)-1-(p-methoxybenzyloxy)-2,6-dimethyl-hept-4-en-3-ol 
• 112057-64-4 (R)-3-(tert-butyldimethylsilyloxy)-2-methylpropan-1-ol 
• 93454-85-4 (S)-3-(tert-butyldimethylsilyloxy)-2-methylpropionic acid methyl ester 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 212051-35-9 (R)-methyl 3-((4-methoxybenzyl)oxy)-2-methylpropanoate 
• 203387-40-0 dimethyl (3R)-3-methyl-4-(p-methoxybenzyloxy)-2-oxobutane-1-phosphonate 

Downstream Products

• 203387-44-4 (2S,3S,6R)-7-(tert-butyl(dimethyl)silyloxy)-3-(p-methoxybenzyloxy)-2,6-dimethylheptan-1-al 
• 668461-34-5 (3R,4S,7R)-8-(tert-butyl(dimethyl)silyloxy)-4-(p-methoxybenzyloxy)-3,7-dimethyl-2-octanol 
• 203387-34-2 (3S,4S,7R)-8-(tert-butyl(dimethyl)silyloxy)-4-(p-methoxybenzyloxy)-3,7-dimethyl-octan-2-one 
• 203387-45-5 (12E,14Z)-(2R,5S,6S,9S,18S)-1-(tert-Butyl-dimethyl-silanyloxy)-18-(tert-butyl-diphenyl-silanyloxy)-9-hydroxy-5-(4-methoxy-benzyloxy)-2,6-dimethyl-nonadeca-12,14-dien-7-one 
• 203387-54-6 (2R,5S,6S,9S,12E,14Z,18S)-18-(tert-butyl(diphenyl)silyloxy)-2,6-dimethyl-5,9-di-(p-methoxybenzyloxy)-7-oxo-nonadeca-12,14-dienal 
• 668461-37-8 (2R,5S,6S,9S,12E,14Z,18S)-18-(tert-butyl(diphenyl)silyloxy)-2,6-dimethyl-5,9-di-(p-methoxybenzyloxy)-1-hydroxynonadeca-12,14-dien-7-one 
• 668461-36-7 (2R,5S,6S,9S,12E,14Z,18S)-1-(tert-butyl(dimethyl)silyloxy)-18-(tert-butyl(diphenyl)silyloxy)-2,6-dimethyl-5,9-di-(p-methoxybenzyloxy)-nonadeca-12,14-dien-7-one 
• 668461-38-9 methyl (4R,7S,8S,11S,14E,16Z,20S)-20-(tert-butyl(diphenyl)silyloxy)-4,8-dimethyl-9-oxo-2,7,11-tri-(p-methoxybenzyloxy)-unicosa-14,16-dienoate 
• 203387-32-0 methyl (4R,7S,8S,11S,14E,16Z,20S)-20-(tert-butyl(diphenyl)silyloxy)-4,8-dimethyl-3,9-dioxo-2,7,11-tri-(p-methoxybenzyloxy)-unicosa-14,16-dienoate 
• 203387-53-5 (2R,3S,6R)-7-(tert-butyl(dimethyl)silyloxy)-3-(p-methoxybenzyloxy)-2,6-dimethylheptan-1-ol 
• 203387-49-9 (2R,3S,6R)-7-(tert-butyl(dimethyl)silyloxy)-2,6-dimethyl-3-(p-methoxybenzyloxy)-1,1-(propan-1',3'-dithio)heptane 

Relevant academic research and scientific papers

Horner-Wadsworth-Emmons reactions as a facile entry to biogenetic key substructures

One-pot Horner-Wadsworth-Emmons reactions are used to synthesize α,β-enones with two configurationally independent stereogenic centers. These intermediates are used for the construction of polyketide and monosaccaride fragments. In particular, novel approaches to the branched pentoses mycarose and arcanose are described.

Studies directed towards the total synthesis of the antibiotic macrodiolide tartrolon: EPC synthesis of the protected seco acid

An efficient synthesis of the protected seco acid 2 of the antibiotic macrodiolide tartrolon 1 is described. Key steps are a substrate controlled aldol-reaction, a Johnson-Claisen rearrangement, and a Horner-Wadsworth-Emmons olefination with subsequent Co