20355-96-8

Upstream product

• 108-88-3 toluene 
• 106-38-7 para-bromotoluene 
• 122-52-1 triethyl phosphite 
• 537-64-4 bis(p-tolyl)mercury 
• 1005-32-9 p-tolyldichlorophosphine 
• 141-52-6 sodium ethanolate 

Downstream Products

• 18788-71-1 p-Tolyl-p-toluoyl-phosphinsaeure-ethylester 
• 64-17-5 ethanol 
• 20783-50-0 p-tolylphosphinic acid 
• 1274901-92-6 C₁₉H₂₀ClO₃P 
• 38766-17-5 ethyl (4-methylphenyl)phosphinate 
• 18788-23-3 Benzoyl-p-tolyl-phosphinsaeure-ethylester 
• 18788-76-6 <2-Chlor-benzoyl>-p-tolyl-phosphinsaeure-ethylester 

Relevant academic research and scientific papers

Efficient Synthesis of Phosphonamidates through One-Pot Sequential Reactions of Phosphonites with Iodine and Amines

A one-pot sequential strategy to construct phosphonamidates has been developed by generating phosphonites in situ from arylmagnesium bromides and triethyl phosphite followed by treatment with iodine and amines. A variety of phosphonamidates were obtained with good to excellent yields at room temperature from easily available materials.

Revisited synthesis of aryl-H-phosphinates

A systematic study of the reaction conditions for the preparation of pure aryl-H-phosphinate esters, originally developed by Sander and optimized by Petnehazy, is reported. The influence of the reaction concentration has been investigated for the formation of phosphonite intermediates via direct addition of triethyl phosphite to the appropriate Grignard reagent. Subsequent hydrolysis of the phosphonites under acidic conditions gives various aryl-H-phosphinates in high yields and purities. Georg Thieme Verlag Stuttgart, New York.

A direct and new convenient oxidation: Synthesis of substituted arylphosphonates from aromatics

An easy synthesis of aryl phosphonates by oxidation from aryldichlorophosphines with iodine in good yields is described. Aryldichlorophosphines are obtained by reaction of phosphorous trichloride with some aromatics in presence of various Lewis acids. BiCl3 and Bi(OTf)3 are used for the first time and bismuth trichloride is, for the first time in the case of anisole or thioanisole phosphonylation, used as a true regenerable Lewis acid catalyst in a reaction of direct phosphonylation of aromatics.