203635-01-2Relevant academic research and scientific papers
Bis-S-acyl-2-thioethyl (SATE)-bearing monophosphate prodrug of β-L-FD4C as potent anti-HBV agent
Li, Xiuyan,Carmichael, Ellen,Feng, Ming,King, Ivan,Doyle, Terrence W.,Chen, Shu-Hui
, p. 57 - 62 (1998)
The S-acyl-2-thioethyl (SATE)-bearing 5'-monophosphate prodrug of β-L-FD4C (8) was synthesized and evaluated for its activity against HBV in the 2.2.15 cell line. This pronucleotide (8) exhibited an excellent inhibitory effect against HBV with an EC5
