Welcome to LookChem.com Sign In|Join Free

Article Doi

Bis-S-acyl-2-thioethyl (SATE)-bearing monophosphate prodrug of β-L-FD4C as potent anti-HBV agent

DOI: 10.1016/S0960-894X(97)10178-0

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 57 - 62 (1998)

Update date:2022-08-04

Topics:

Authors:

Li, XiuyanLi, Xiuyan

Carmichael, EllenCarmichael, Ellen

Feng, MingFeng, Ming

King, IvanKing, Ivan

Doyle, Terrence W.Doyle, Terrence W.

Chen, Shu-HuiChen, Shu-Hui

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(97)10178-0

The S-acyl-2-thioethyl (SATE)-bearing 5'-monophosphate prodrug of β-L-FD4C (8) was synthesized and evaluated for its activity against HBV in the 2.2.15 cell line. This pronucleotide (8) exhibited an excellent inhibitory effect against HBV with an EC5

View More

Full text of DOI:10.1016/S0960-894X(97)10178-0

Products guided by the article

Product name:{1-[(2S,5R)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-2,5-dihydro-furan-2-yl]-5-fluoro-2-oxo-1,2-dihydro-pyrimidin-4-yl}-carbamic acid 2,2,2-trichloro-ethyl ester

Cas No:203635-01-2

203635-01-2

R&D Labs maybe for 203635-01-2

Relevant to this article

Hot Product