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Benzamide, N-[2-[4-[[[(cyclohexylamino)-carbonyl]amino]sulfonyl]phenyl]ethyl]-4-methoxy- is a complex organic compound with the molecular formula C22H28N4O5S2. It is a derivative of benzamide, featuring a cyclohexane ring and a sulfonyl group attached to the benzene ring. The compound also contains an ethyl chain with a 4-methoxy group and an aminosulfonylphenyl group. This chemical is known for its potential applications in pharmaceuticals, particularly as an intermediate in the synthesis of certain drugs. Its structure provides a range of functional groups that can participate in various chemical reactions, making it a versatile building block in organic synthesis.

2037-67-4

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2037-67-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2037-67-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,0,3 and 7 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 2037-67:
(6*2)+(5*0)+(4*3)+(3*7)+(2*6)+(1*7)=64
64 % 10 = 4
So 2037-67-4 is a valid CAS Registry Number.

2037-67-4Downstream Products

2037-67-4Relevant academic research and scientific papers

Synthesis and evaluation of α-glucosidase inhibitory activity of sulfonylurea derivatives

Bui, Thi Thoi,Tran, Van Loc,Ngo, Dai Quang,Tran, Van Chien,Tran, Van Sung,Tran, Thi Phuong Thao

, p. 163 - 171 (2021/03/16)

Two series of sulfonylureas derivatives including 24 compounds (4, 7, 5a-5o, 8a-8h), among them 17 new derivatives, have been synthesized and evaluated for their α-glucosidase inhibitory activity. Compounds 5c, 5h and 8e showed significant in vitro α-glucosidase inhibition with IC50 values of 5.58, 79.85 and 213.36 μm, respectively, comparing with the standard compounds acarbose (IC50 = 268.29 μm) and glipizide (IC50 = 300.47 μm). The preliminary structure-activity relationships (SARs) of the synthesized compounds were also investigated.

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