20375-42-2Relevant articles and documents
Effects of double photoreactions on polycoumarate photomechanics
Yasaki, Katsuaki,Suzuki, Takuya,Yazawa, Koji,Kaneko, Daisaku,Kaneko, Tatsuo
, p. 1112 - 1118 (2011)
We established a polymerization condition of 3-hydroxycinnamic acid, 3HCA, having photoreactive units over all the main chains. The polymers showed two types of photoreaction, that is, intramolecular E-Z isomerization and interchain [2 + 2] cycloaddition. Spectroscopic studies showed that the rate of the isomerization was higher than that of the cycloaddition. Although the original fiber was very brittle, the short-time UV-irradiation made the fiber softer and more elastic because the chain bending by the isomerization preferentially occurred. On the other hand, the long-time irradiation made the fiber harder because of the cross-linking by the cycloaddition, and simultaneously enhanced the elasticity. Besides we found that the cast film of P3HCA showed a photo-bending behavior with the convex surface facing the UV-lamp by the initial E-Z isomerization.
METHOD OF PRODUCING BENZOIC ACID
-
Paragraph 0133-0136, (2016/10/08)
PROBLEM TO BE SOLVED: To provide a novel synthesis method in the production of a benzoic acid, which is an important compound for the synthesis of an organic compound, and an industrially suitable production method using main materials derived from nonfossil resources. SOLUTION: This invention provides a method of producing a benzoic acid with a substituted hydroxyl group, methoxy group, or acetoxy group, comprising the step of the ozonation of a compound represented by formula (I), where R1 is H, a methyl group or an acetyl group; R2 is H or an acetoxy group; R3 is an alkyl group, a carboxy group, a formyl group, an alkoxycarbonyl group, an amide group, an acid chloride group, a halogenation alkyl group, or a hydroxyalkyl group. COPYRIGHT: (C)2015,JPOandINPIT
The design, synthesis and in vitro immunosuppressive evaluation of novel isobenzofuran derivatives
Yang, Na,Wang, Qing-He,Wang, Wen-Qian,Wang, Jian,Li, Feng,Tan, Shen-Peng,Cheng, Mao-Sheng
body text, p. 53 - 56 (2012/02/16)
The synthesis and biological evaluation of a series of novel isobenzofuran-based compounds are described. The compounds were evaluated for their immunosuppressive effects of T-cell proliferation and IMPDH type II inhibitor activity in vitro, as well as their structure-activity relationships were assessed. Several compounds demonstrated highly efficacious immunosuppressive properties, especially compounds 2d, 2e, 2h and 2j, which were superior to MPA, while compounds 2k, 2m, 2n, 4c and 5d exhibited an equipotent inhibitory activity compared to MPA. Generally, it was obviously demonstrated that α,β-unsaturated amides proved more potent than the diamide and urea series. The present study provides a guide for further research on development of safe and effective immunosuppressive agents.
