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1-Aminopyrrolidin-2-one hydrochloride is an organic compound that serves as a key intermediate in the synthesis of various pharmaceuticals and bioactive molecules. It is characterized by its unique structure, which includes a pyrrolidinone ring and an amino group, making it a versatile building block in medicinal chemistry.

20386-22-5

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20386-22-5 Usage

Uses

Used in Pharmaceutical Industry:
1-Aminopyrrolidin-2-one hydrochloride is used as a chemical intermediate for the optimization of the dihydropyrrolopyrazole series. This series is crucial in the development of transforming growth factor-β (TGF-β) type I receptor kinase domain inhibitors, which play a significant role in regulating cellular processes and have potential applications in treating various diseases.
Additionally, 1-Aminopyrrolidin-2-one hydrochloride is used as a precursor in the discovery and synthesis of orally bioavailable antitumor agents. These agents have the potential to be effective in treating cancer by targeting specific molecular pathways involved in tumor growth and progression, offering a promising avenue for cancer therapy.

Check Digit Verification of cas no

The CAS Registry Mumber 20386-22-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,3,8 and 6 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 20386-22:
(7*2)+(6*0)+(5*3)+(4*8)+(3*6)+(2*2)+(1*2)=85
85 % 10 = 5
So 20386-22-5 is a valid CAS Registry Number.

20386-22-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-aminopyrrolidin-2-one,hydrochloride

1.2 Other means of identification

Product number -
Other names N-aminopyrrolidone hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:20386-22-5 SDS

20386-22-5Relevant academic research and scientific papers

POLYAROMATIC UREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF MUSCLE DISEASES

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Page/Page column 125, (2021/01/29)

The current invention provides urea derivatives, in particular compounds having the core structure heteroaryl-NH-CO-NH-aryl-O- heteroaryl, for use in treating, ameliorating, delaying, curing and/ or preventing a disease or condition associated with muscle cells and/or satellite cells, such as Duchenne muscular dystrophy, Becker muscular dystrophy, cachexia or sarcopenia.

Bicyclic Pyridinylpyrazoles

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Page/Page column 32, (2011/10/19)

Bicyclic pyridinylpyrazoles of the formula (I) in which the symbols have the meanings given in the description and agrochemically active salts thereof and their use for controlling unwanted microorganisms in crop protection and the protection of materials

MIXED LINEAGE KINASE MODULATORS

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Page 39-40, (2008/06/13)

The present invention provides a compound of the formula: (Formula I); or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising an effective amount of a compound of Formula I in combination with a suitable carrier, diluent, or excipient, and methods for treating physiological disorders, particularly congestive heart disease, comprising administering to a patient in thereof an effective amount of a compound of Formula I.

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