79289-48-8

Usage

Uses

Used in Pharmaceutical Industry:
1,2-Pyrrolidinedione, ,-diphenyl-, 1-one is used as a chemical intermediate for the synthesis of various drugs and pharmaceuticals, contributing to the development of new medications and therapeutic agents.
Used in Organic Compound Production:
1,2-Pyrrolidinedione, ,-diphenyl-, 1-one is also utilized as a building block in the production of other organic compounds, playing a crucial role in the synthesis of complex organic molecules for various applications.

Upstream product

• 119-61-9 benzophenone 
• 5350-57-2 benzophenone hydrazone 
• 79289-25-1 benzophenone δ-chlorobutyrylhydrazone 

Downstream Products

• 20386-22-5 1-aminopyrrolidin-2-one hydrochloride 
• 924898-12-4 1-(amino)-2-pyrollidinone p-toluenesulfonate 

Relevant academic research and scientific papers

POLYAROMATIC UREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF MUSCLE DISEASES

The current invention provides urea derivatives, in particular compounds having the core structure heteroaryl-NH-CO-NH-aryl-O- heteroaryl, for use in treating, ameliorating, delaying, curing and/ or preventing a disease or condition associated with muscle cells and/or satellite cells, such as Duchenne muscular dystrophy, Becker muscular dystrophy, cachexia or sarcopenia.

Bicyclic Pyridinylpyrazoles

Bicyclic pyridinylpyrazoles of the formula (I) in which the symbols have the meanings given in the description and agrochemically active salts thereof and their use for controlling unwanted microorganisms in crop protection and the protection of materials

MIXED LINEAGE KINASE MODULATORS

The present invention provides a compound of the formula: (Formula I); or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising an effective amount of a compound of Formula I in combination with a suitable carrier, diluent, or excipient, and methods for treating physiological disorders, particularly congestive heart disease, comprising administering to a patient in thereof an effective amount of a compound of Formula I.

Synthesis and properties of 3-oxo-1,2-diazetidinium ylides

Treatment of α-chloroacylhydrazones of diaryl and certain aralkyl and dialkyl ketones with sodium hydride in anhydrous tetrahydrofuran gives 1-(disubstituted methylene)-3-oxo-1,2-diazetidinium inner salts (ylides). The reaction pathway involves formation of the hydrazone anion followed by intramolecular SN2 halide displacement (with complete inversion at the α carbon) by the sp2 imine nitrogen. These 1-(disubstituted methylene)-3-oxo-1,2-diazetidinium ylides are reduced by sodium borohydride to give 1-substituted 1,2-diazetidin-3-ones, undergo dipolar cycloaddition reactions to give fused aza-β-lactams, and can be hydrolyzed with p-toluenesulfonic acid monohydrate to the p-toluenesulfonic acid salt of 1,2-diazetidinone.