204056-65-5Relevant academic research and scientific papers
Synthesis and activities of bactobolin derivatives based on the alteration of the functionality at C-3 position
Adachi, Hayamitsu,Usui, Takayuki,Nishimura, Yoshio,Kondo, Shinichi,Ishizuka, Masaaki,Takeuchi, Tomio
, p. 184 - 188 (1998)
Some derivatives of bactobolin were prepared from bactobolin (1) by radical reduction and formation of the fused azetidine ring. The derivatives proved less active than the parent antibiotic 1 against bacteria, indicating that dichloromethyl group at C-3 position play an important role in biological activity.
