204059-97-2

Upstream product

• 4070-48-8 L-Valine methyl ester 
• 2258-42-6 formyl acetic anhydride 
• 204059-95-0 (S)-methyl 3-methyl-2-(phenylamino)butanoate 

Downstream Products

• 219638-96-7 (S)-N-methyl-N-phenyl-2-amino-3-methylbutan-1-ol 
• 219638-97-8 (S)-N-methyl-N-phenyl-2-amino-3-methyl-1-thiolacetylbutane 
• 204059-93-8 (S)-N-methyl-N-phenyl-2-amino-3-methylbutan-1-thiol 

Relevant academic research and scientific papers

The importance of nitrogen substituents in chiral amino thiol ligands for the asymmetric addition of diethylzinc to aromatic aldehydes

A new series of N,S-chelate ligands derived from (S)-valine, which possess the capability of a stereogenic nitrogen donor atom, are catalysts for the addition of diethylzinc to aromatic aldehydes and gave the product secondary alcohols in up to 82% ee.

Concepts for ligand design in asymmetric catalysis: A study of chiral amino thiol ligands

A series of new chiral sulfur-nitrogen chelate ligands, derived from amino acids, has been synthesised rationally. Fruitless experiments into catalytic asymmetric conjugate additions and desymmetrisation of meso- epoxides led us to analyse our ligands in