204066-65-9Relevant academic research and scientific papers
4-Alkyl- and 4-cinnamylglutamic acid analogues are potent GluR5 kainate receptor agonists
Pedregal, Concepción,Collado, Iván,Escribano, Ana,Ezquerra, Jesús,Dominguez, Carmen,Mateo, Ana I.,Rubio, Almudena,Baker, S. Richard,Goldsworthy, John,Kamboj, Rajender K.,Ballyk, Barbara A.,Hoo, Ken,Bleakman, David
, p. 1958 - 1968 (2000)
Enantiomerically pure (2S,4R)-4-substituted glutamic acids were prepared and tested for homomeric GluR5 and GluR6 kainate subtype receptor affinity. Some of the 4-cinnamyl analogues showed high selectivity and potency (K(i) 25 nM) for the GluR5 receptor
