204068-77-9

Upstream product

• 13096-62-3 (3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2-one 
• 133697-34-4 2,6-anhydro-3,4,5,7-tetra-O-benzyl-1-deoxy-D-gluco-hept-1-enitol 
• 6564-72-3 2,3,4,6-tetra-O-benzyl-D-glucopyranose 
• 113019-43-5 2,3,4,6-tetra-O-benzyl-1-formyl-D-glucopyranose 
• 93414-71-2 2'-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)furan 
• 89064-71-1 β-C-(hydroxymethyl)-2,3,4,6-tetra-O-benzyl-β-D-glucopyranoside 

Downstream Products

• 1063748-61-7 methyl 4,6-O-benzylidene-2-deoxy-2-[(N'-2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)ureido]-α-D-glucopyranoside 
• 1063748-67-3 methyl 2,3,4-tri-O-benzyl-6-deoxy-6-[(N'-2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)ureido]-α-D-glucopyranoside 
• 1063748-01-5 2,3,4,6-tetra-O-benzyl-1-O-[(N-2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)carbamoyl]-β-D-glucopyranoside 
• 869500-66-3 2,6-anhydro-3,4,5,7-tetra-O-benzyl-1-C-trimethylsilylethynyl-aldehydo-D-glycero-D-gulo-heptose 

Relevant academic research and scientific papers

Highly stereoselective synthesis of aryl/heteroaryl-: C -nucleosides via the merger of photoredox and nickel catalysis

A photoredox/nickel dual-catalyzed decarboxylative cross-coupling reaction of anomeric ribosyl/deoxyribosyl acids with aryl/heteroaryl bromides has been developed. The reaction proceeds smoothly under visible-light irradiation and features the using of cost-effective and easily handled catalysts and starting materials, which allows the highly stereoselective synthesis of diverse aryl/heteroaryl-C-nucleosides in moderate to high yields.

Acyl and Benzyl-C-β-D-Glucosides: Synthesis and Biostudies for Glucose-Uptake-Promoting Activity in C2C12 Mytotubes

A convenient and scalable synthetic approach has been developed for the synthesis of acyl-C-β-d-glucosides and benzyl-C-β-d-glucosides. The use of Weinreb-amide (WA) functionality was crucial for this accomplishment as the other apparently capable alternatives, had severe limitations for the access to acyl-C-glucosides. The synthesized compounds, acyl and benzyl-C-glucosides promote glucose-uptake activity in the C2C12 (mouse skeletal muscle) cell lines through PPAR-γ mediated GLUT4 expression. The developed synthetic scheme for acyl-and benzyl-C-β-d-glucosides and biostudies evaluating their activity as glucose-uptake promoters are disclosed herein.

Novel synthesis of oligosaccharides linked with carbamate and urea bonds utilizing modified Curtius rearrangement

We describe a novel synthesis of various carbamate- and urea-linked disaccharides stereospecifically using sugar carboxylic acids and sugar alcohols or sugar amines by the modified Curtius rearrangement. In this reaction, the reactivity of each hydroxyl g

An access to glycoconjugate libraries through multicomponent reactions

Four-component reactions: The Ugi reaction of four suitably functionalized carbohydrate derivatives (as a per-O-benzylated amine, an aldehyde, a carboxylic acid, and an isocyanide) allow the effective assembly of diverse compound libraries. The complex gl

Furan-based synthesis of C-glycosyl carboxylates

The installation of the 2-furyl ring at the anomeric carbon of 2,3,4,6-tetra-O-benzyl-D-glucopyronose and 2,3:5,6-di-O-isopropylidene-D-mannofuranose is carried out either by addition of 2-lithiofuran to the corresponding lactones either by direct C-glyco