20416-16-4

Basic information

• Product Name: (3-Methyl-2-furyl)methanol
• Synonyms: (3-Methyl-2-furyl)methanol;2-(Hydroxymethyl)-3-methylfuran 97%;2-(Hydroxymethyl)-3-methylfuran;(3-Methylfur-2-yl)methanol;2-(Hydroxymethyl)-3-methylfuran97%
• CAS NO: 20416-16-4
• Molecular Formula: C₆H₈O₂
• Molecular Weight: 112.13
• Mol File: 20416-16-4.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 185.3°Cat760mmHg
• Flash Point: 65.8°C
• Appearance: /
• Density: 1.095g/cm³
• Vapor Pressure: 0.452mmHg at 25°C
• Refractive Index: 1.494
• PKA: 14.05±0.10(Predicted)
• CAS DataBase Reference: (3-Methyl-2-furyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (3-Methyl-2-furyl)methanol(20416-16-4)
• EPA Substance Registry System: (3-Methyl-2-furyl)methanol(20416-16-4)

Safety Data

• Hazardous Substances Data: 20416-16-4(Hazardous Substances Data)

Usage

General Description

(3-Methyl-2-furyl)methanol, also known as 3-methyl-2-furylmethanol or 3-MF, is a chemical compound with a molecular formula C6H8O2. It is an aromatic alcohol and has a furan ring in its chemical structure, making it a derivative of furfural. (3-Methyl-2-furyl)methanol is known for its sweet, caramel-like odor and is commonly used as a flavoring agent in the food industry. It is also an important intermediate in the synthesis of various pharmaceuticals and agrochemicals. However, it is important to note that (3-Methyl-2-furyl)methanol is toxic and should be handled with care, as it has the potential to cause skin and eye irritation upon contact.

InChI:InChI=1/C6H8O2/c1-5-2-3-8-6(5)4-7/h2-3,7H,4H2,1H3

Upstream product

• 33342-48-2 3-methyl-2-furfuraldehyde 
• 84374-68-5 3-methyl-furan-2-carbonitrile 
• 488-93-7 3-Furoic acid 
• 4412-91-3 furan-3-methanol 
• 14497-29-1 3-(chloromethyl)furan 
• 50-00-0 formaldehyd 
• 6141-57-7 methyl 3-methylfuran-2-carboxylate 
• 4412-96-8 3-methylfuran-2-carboxylic acid 

Downstream Products

• 79204-33-4 benzoic acid 3-methyl-furan-2-ylmethyl ester 
• 33342-48-2 3-methyl-2-furfuraldehyde 
• 1403651-05-7 2-methyl-N-((3-methylfuran-2-yl)(p-tolyl)methyl)-N-(prop-2-ynyl)propane-2-sulfonamide 
• 1403651-41-1 2-methyl-N-((3-methylfuran-2-yl)(p-tolyl)methyl)propane-2-sulfonamide 
• 1403651-40-0 2-methyl-N-((3-methylfuran-2-yl)(p-tolyl)methyl)propane-2-sulfinamide 
• 1403651-04-6 N-((4-methoxyphenyl)(3-methylfuran-2-yl)methyl)-2-methyl-N-(prop-2-ynyl)propane-2-sulfonamide 
• 1403651-38-6 N-((4-methoxyphenyl)(3-methylfuran-2-yl)methyl)-2-methylpropane-2-sulfonamide 
• 1403651-37-5 N-((4-methoxyphenyl)(3-methylfuran-2-yl)methyl)-2-methylpropane-2-sulfinamide 
• 1093944-21-8 2-methyl-N-[(3-methylfuran-2-yl)(phenyl)methyl]-N-prop-2-yn-1-ylpropane-2-sulfonamide 
• 1093944-09-2 2-methyl-N-[(3-methylfuran-2-yl)(phenyl)methyl]-2-propane-2-sulfonamide 
• 1403651-03-5 N-((4-methoxyphenyl)(3-methylfuran-2-yl)methyl)-N-tosylprop-2-yn-1-amine 
• 1403651-34-2 (4-methoxyphenyl)(3-methylfuran-2-yl)-N-tosylmethanamine 
• 1403651-33-1 (3-methylfuran-2-yl)-N-tosylmethanimine 
• 1403650-94-1 2-(2,5-dihydro-5-phenylfuran-3-yl)-3-methylfuran 

Relevant articles and documents

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Synthesis of a highly functionalized core of verrillin

An efficient stereoselective synthesis of furanoverrillin (5), a highly functionalized core of verrillin (1), is reported. The synthetic strategy is based on constructing bicyclic lactone 17 prior to the 10-membered ring macrocyclization. The effect of the C4 methyl group on the furan reactivity is also discussed.

Enantioconvergent Biocatalytic Redox Isomerization

Alcohol dehydrogenases can act as powerful catalysts in the preparation of optically pure γ-hydroxy-δ-lactones by means of an enantioconvergent dynamic redox isomerization of readily available Achmatowicz-type pyranones. Imitating the traditionally metal-

Pd-catalyzed reaction of aryl halides and propargyl furylmethyl ethers: A novel pathway to functionalized dihydroisobenzofurans

An interesting sequential reaction involving Sonogashira coupling, propargyl-allenyl isomerization, intramolecular [4 + 2] cycloaddition, and bridged oxa-ring opening has been realized, providing a facile method for the synthesis of functionalized dihydroisobenzofurans from easily accessible starting materials with a decent diastereoselectivity.