2043-10-9 Usage
General Description
The chemical compound (dichloromethyl)(dimethyl)silyl, also known as trimethylsilyldichloromethane, is a silylating agent commonly used in organic synthesis and as a protective group for alcohols and amines. It consists of a silicon atom bonded to three methyl groups and two chlorine atoms, and is highly reactive towards nucleophilic substitution reactions. It is also useful in the synthesis of organosilicon compounds and in the modification of biomolecules for various research and industrial applications. Overall, (dichloromethyl)(dimethyl)silyl is an important reagent in organic chemistry with versatile applications in the field of synthetic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 2043-10-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,0,4 and 3 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2043-10:
(6*2)+(5*0)+(4*4)+(3*3)+(2*1)+(1*0)=39
39 % 10 = 9
So 2043-10-9 is a valid CAS Registry Number.
2043-10-9Relevant articles and documents
Simplified preparations of trialkylsilyl- and bis(trialkylsilyl)dihalomethanes via the deprotonation of dihalomethanes
Yoon, Kunsang,Son, David Y.
, p. 185 - 189 (1997)
Simple, high-yield routes to trialkylsilyl- and bis(trialkylsilyl)dihalomethanes are described. These compounds are prepared by the deprotonation of dibromomethane or dichloromethane by lithium diisopropylamide in the presence of a chlorosilane. The reactions are carried out at temperatures below - 70°C in THF/hexane solvent mixtures. After aqueous workup, the air- and water-stable products are isolated by either distillation or crystallization. Further reactions on these compounds are possible, as illustrated by one example.
