20443-75-8 Usage
General Description
4'-Nitro-biphenyl-4-sulfonyl chloride, also known as 4-nitrobiphenyl-4-sulfonyl chloride, is a chemical compound with the molecular formula C12H8ClNO4S. It is a yellow solid that is primarily used as an intermediate in the pharmaceutical industry for the synthesis of various drugs. 4'-NITRO-BIPHENYL-4-SULFONYL CHLORIDE is a sulfonyl chloride derivative of nitrobiphenyl, which makes it useful for the introduction of the nitrophenylsulfonyl group into other molecules. It is also used in organic synthesis as a reagent for the preparation of various organic compounds and is an important building block in the production of pharmaceuticals and agrochemicals. Additionally, it has applications in the manufacturing of dyes, pigments, and other specialty chemicals. However, it is important to handle this compound with care, as it is corrosive and can cause skin and eye irritation upon contact.
Check Digit Verification of cas no
The CAS Registry Mumber 20443-75-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,4,4 and 3 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 20443-75:
(7*2)+(6*0)+(5*4)+(4*4)+(3*3)+(2*7)+(1*5)=78
78 % 10 = 8
So 20443-75-8 is a valid CAS Registry Number.
20443-75-8Relevant articles and documents
Biaryl sulfonamides and methods for using same
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Page/Page column 27, (2010/02/12)
The present invention relates to biaryl sulfonamides and their use as, for example, metalloproteinase inhibitors.
Synthesis of radiolabeled biphenylsulfonamide matrix metalloproteinase inhibitors as new potential PET cancer imaging agents
Fei, Xiangshu,Zheng, Qi-Huang,Liu, Xuan,Wang, Ji-Quan,Sun, Hui Bin,Mock, Bruce H.,Stone, K. Lee,Miller, Kathy D.,Sledge, George W.,Hutchins, Gary D.
, p. 2217 - 2222 (2007/10/03)
Novel matrix metalloproteinase (MMP) inhibitor radiotracers, (S)-3-methyl-2-(2′,3′,4′-methoxybiphenyl-4-sulfonylamino)- butyric acid [11C]methyl ester (1a-c), (S)-3-methyl-2-(2′,3′,4′-fluorobiphenyl-4-sulfonylamino)- butyric acid [11C]methyl ester (1d-f), and (S)-3-methyl-2-(4′-nitrobiphenyl-4-sulfonylamino)-butyric acid [11C]methyl ester (1g), a series of substituted biphenylsulfonamide derivatives, have been synthesized for evaluation as new potential positron emission tomography (PET) cancer imaging agents.
