204444-56-4

Basic information

• Product Name: 4-bromo-2-methyl-1-(2-iodoophenacyl)-5-nitroimidazole
• Synonyms: 4-bromo-2-methyl-1-(2-iodoophenacyl)-5-nitroimidazole
• CAS NO: 204444-56-4
• Molecular Weight: 450.03
• Mol File: 204444-56-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-bromo-2-methyl-1-(2-iodoophenacyl)-5-nitroimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-2-methyl-1-(2-iodoophenacyl)-5-nitroimidazole(204444-56-4)
• EPA Substance Registry System: 4-bromo-2-methyl-1-(2-iodoophenacyl)-5-nitroimidazole(204444-56-4)

Safety Data

• Hazardous Substances Data: 204444-56-4(Hazardous Substances Data)

Upstream product

• 113258-84-7 2-bromo-1-(2-iodophenyl)ethanone 
• 18874-52-7 5-bromo-2-methyl-4-nitro-1H-imidazole 
• 31827-94-8 2-bromo-1-(4-iodophenyl)ethanone 
• 18874-52-7 4-bromo-2-methyl-5-nitroimidazole 

Downstream Products

• 204444-58-6 5-bromo-1-(4-iodophenacyl)-2-methyl-4-nitroimidazole 

Relevant articles and documents

NOVEL DERIVATIVES OF IMIDAZOLE, USE OF NOVEL DERIVATIVES OF IMIDAZOLE AND A METHOD OF MANUFACTURING THEM

Novel derivatives of imidazole, a method of manufacturing them as well as their use as the active substance in medicinal products for use in human and veterinary medicine have been disclosed.

Synthesis of some 5-amino-2-methyl-4-nitro-1-phenacylimidazoles

Reaction of 4(5)-bromo-2-methyl-5(4)-nitroimidazole with phenacyl bromide derivatives gave two isomers: 4-bromo-5-nitroimidazoles (4a-e) and 5-bromo-4-nitroimidazoles (5a-e). Compounds 5a-e were treated with cyclic secondary amines to afford expected 5-amino-4-nitroimidazole derivatives 6a-c - 10a-b.