204449-03-6Relevant articles and documents
A short and efficient synthesis of 4-[2,2-dimethyl-4(tol-4- yl)benzochrom-3-en-7-yl]benzoic acid - A potent retinoic acid receptor antagonist
Vuligonda, Vidyasagar,Chandraratna, Roshantha A.S.
, p. 2289 - 2290 (2007/10/03)
An efficient synthesis of a potent RAR antagonist is described starting from disubstituted β-naphthol. The functional groups on 2 and 3 positions of the β-naphthol 5 were elaborated into benzochromanone 8. The title compound was prepared by Suzuki coupling of the left and right hand pieces.