247599-79-7

Upstream product

• 123266-62-6 7-bromo-3-methoxy-2-naphthoic acid 
• 123266-51-3 7-bromo-3-methoxynaphthalene-2-carboxylic acid methyl ester 
• 261516-37-4 1-(7-bromo-3-methoxy-naphthalen-2-yl)-ethanone 
• 247599-77-5 1-(7-bromo-3-hydroxy-naphthalen-2-yl)-ethanone 
• 247599-78-6 7-bromo-2,2-dimethyl-2,3-dihydro-benzo[g]chromen-4-one 

Downstream Products

• 204449-03-6 4-(2,2-dimethyl-4-p-tolyl-2H-benzo[g]chromen-7-yl)-benzoic acid ethyl ester 

Relevant academic research and scientific papers

A short and efficient synthesis of 4-[2,2-dimethyl-4(tol-4- yl)benzochrom-3-en-7-yl]benzoic acid - A potent retinoic acid receptor antagonist

An efficient synthesis of a potent RAR antagonist is described starting from disubstituted β-naphthol. The functional groups on 2 and 3 positions of the β-naphthol 5 were elaborated into benzochromanone 8. The title compound was prepared by Suzuki coupling of the left and right hand pieces.