20445-24-3

Upstream product

• 20445-31-2 R-(+)-α-trifluoromethyl-α-methoxy-phenylacetic acid 
• 156-34-3 l-amphetamine 
• 60-15-1 2-amino-1-phenylpropane 
• 100-52-7 benzaldehyde 
• 64312-89-6 Mosher's acid chloride 
• 705-60-2 (2-nitroprop-1-enyl)benzene 
• 162929-45-5 C₁₂H₁₇NO₂ 

Relevant academic research and scientific papers

Enzymatic enantiomeric resolution of phenylethylamines structurally related to amphetamine

Both enantiomers of several phenylethylamines, structurally related to amphetamine, have been prepared in good yields and excellent enantiomeric purity by enzymatic kinetic resolution using CAL-B and ethyl methoxyacetate as the acyl donor. In the case of the 4-hydroxyderivative of amphetamine (compound 4i), the S enantiomer racemized possibly in a dynamic kinetic resolution (DKR) under the enzymatic conditions used. The Royal Society of Chemistry 2011.

Conversion of chiral amino acids to enantiomerically pure α-methylamines

Enantiomerically enriched α-methylamines are obtained in high yield by Raney nickel reduction of N-Boc-protected, amino acid-derived thioethers.