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204452-91-5

204452-91-5

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204452-91-5 Usage

General Description

7-DIMETHOXYMETHYL-1,2,3,4-TETRAHYDRO-[1,8]NAPHTHYRIDINE is a chemical compound with the molecular formula C15H19NO2. It is a member of the naphthyridine family and contains two methoxy and one dimethoxy groups. 7-DIMETHOXYMETHYL-1,2,3,4-TETRAHYDRO-[1,8]NAPHTHYRIDINE has potential biological activity and may have applications in pharmaceutical and medicinal chemistry. Its specific properties and potential uses would require further research and testing.

Check Digit Verification of cas no

The CAS Registry Mumber 204452-91-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,4,4,5 and 2 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 204452-91:
(8*2)+(7*0)+(6*4)+(5*4)+(4*5)+(3*2)+(2*9)+(1*1)=105
105 % 10 = 5
So 204452-91-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H16N2O2/c1-14-11(15-2)9-6-5-8-4-3-7-12-10(8)13-9/h5-6,11H,3-4,7H2,1-2H3,(H,12,13)

204452-91-5 Well-known Company Product Price

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  • Aldrich

  • (ADE000835)  7-Dimethoxymethyl-1,2,3,4-tetrahydro-[1,8]naphthyridine  AldrichCPR

  • 204452-91-5

  • ADE000835-1G

  • 1,930.50CNY

  • Detail

204452-91-5Relevant articles and documents

Design, Synthesis, and Biological Evaluation of 2-Formyl Tetrahydronaphthyridine Urea Derivatives as New Selective Covalently Reversible FGFR4 Inhibitors

Chen, Hao,Ding, Ke,Huang, Jing,Li, Jie,Peng, Lijie,Tu, Zheng-Chao,Zhang, Zhang,Zhang, Zhen,Zhou, Yang

, p. 3249 - 3265 (2022/02/16)

Aberrant FGF19/FGFR4 signaling is an oncogenic driver force for the development of human hepatocellular carcinoma (HCC). A series of 2-formyl tetrahydronaphthyridine urea derivatives were designed and synthesized as new covalently reversible inhibitors of

Characterization of an aromatic trifluoromethyl ketone as a new warhead for covalently reversible kinase inhibitor design

Zhang, Zhen,Wang, Yongjin,Chen, Xiaojuan,Song, Xiaojuan,Tu, Zhengchao,Chen, Yongheng,Zhang, Zhimin,Ding, Ke

, (2021/10/21)

An aromatic trifluoromethyl ketone moiety was characterized as a new warhead for covalently reversible kinase inhibitor design to target the non-catalytic cysteine residue. Potent and selective covalently reversible inhibitors of FGFR4 kinase were success

FGFR4 INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF

-

, (2019/02/28)

The present invention relates to an FGFR4 inhibitor having a structure represented by formula (I), preparation method therefor, and applications thereof. A series of compounds represented by formula (I) in the present invention have a very-strong inhibiti

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