2045-25-2

Usage

Uses

Used in Medicinal Chemistry:
2-AMINO-4-MORPHOLINO-S-TRIAZINE is used as a key intermediate for the synthesis of pharmaceuticals due to its ability to be incorporated into complex molecular structures, enhancing the development of new drugs with improved therapeutic properties.
Used in Agrochemical Production:
In the agrochemical industry, 2-AMINO-4-MORPHOLINO-S-TRIAZINE is utilized as a building block for the creation of novel agrochemicals, potentially leading to more effective and targeted pest control solutions.
Used in Drug Discovery:
2-AMINO-4-MORPHOLINO-S-TRIAZINE is employed as a valuable tool in drug discovery, where its unique structure allows for the exploration of new chemical spaces and the design of innovative therapeutic agents.
Used in Organic Synthesis:
As a versatile building block, 2-AMINO-4-MORPHOLINO-S-TRIAZINE is used in organic synthesis for the creation of a wide range of organic compounds, contributing to the advancement of chemical research and the development of new materials.

InChI:InChI=1/C7H11N5O/c8-6-9-5-10-7(11-6)12-1-3-13-4-2-12/h5H,1-4H2,(H2,8,9,10,11)

Upstream product

• 77287-34-4 formamide 
• 3731-59-7 moroxydine 
• 68-12-2 N,N-dimethyl-formamide 
• 109-94-4 formic acid ethyl ester 
• 124-41-4 sodium methylate 
• 3160-91-6 moroxydine hydrochloride 

Downstream Products

• 63671-32-9 4-chloro-N-(4-morpholin-4-yl-[1,3,5]triazin-2-yl)-benzenesulfonamide 
• 63671-29-4 N-(4-morpholin-4-yl-[1,3,5]triazin-2-yl)-benzenesulfonamide 
• 63671-30-7 N-(4-morpholin-4-yl-[1,3,5]triazin-2-yl)-toluene-4-sulfonamide 
• 63671-31-8 4-methoxy-N-(4-morpholin-4-yl-[1,3,5]triazin-2-yl)-benzenesulfonamide 

Relevant academic research and scientific papers

Metal free [4+1] and [5+1] annulation reactions to prepare heterocycles using DMF and its derivatives as one-carbon source

1,2,4-Triazolo[3,4-a]pyridines and related heterocycles and substituted triazines were commonly discovered scaffolds in a variety of pharmaceutical and agrochemical agents. Herein, we report a highly efficient and practical method using DMF and its derivative for the [4+1] and [5+1] annulation reactions to prepare these heterocycles. This metal free reaction takes advantages of shelf stable DMF as solvent and carbon donor, imidazole chloride as a catalyst, the mild reaction condition tolerates a broad substrate range and substitutes. The prepared 3-unsubstituted 1,2,4-triazolo[3,4-a]pyridine and derivatives allow further introduction of a variety of functional group1 at 3-position.

N-(2-guanidino-ethylimino)-morpholine antigen based on thiotriazinone structure restrictiveness, antibody and application

The present invention discloses a N-(2-guanidino-ethylimino)-morpholine hapten based on thiotriazinone structure restrictiveness, an artificial antigen, an antibody and an application. The structure of the N-(2-guanidino-ethylimino)-morpholine hapten is represented by a formula I shown in the description, wherein R is -H and -CH3. The N-(2-guanidino-ethylimino)-morpholine artificial antigen and antibody are prepared base on the hapten, and the artificial antigen and antibody have high detection efficiency and simple operation to N-(2-guanidino-ethylimino)-morpholine, and can be used in enzyme-linked immunosorbent assay rapid detection of the N-(2-guanidino-ethylimino)-morpholine; and the antigen and the antibody have a simple synthetic process, lower costs, and good application prospects.

Regioselective synthesis of imidazo[1,2-a][1,3,5]triazines and 3,4-dihydroimidazo[1,2-a][1,3,5]triazines from [1,3,5]triazin-2,4-diamines

An efficient and practical procedure was developed to prepare novel imidazo[1,2-a][1,3,5]triazines and 3,4-dihydroimidazo[1,2-a][1,3,5]triazines with a good regioselectivity and high yields, starting from dicyandiamide and the corresponding arylamines. Mechanistic studies for the subsequent cyclocondensation with chloroacetaldehyde support a pathway, which begins with the displacement of the chloro atom activated by an adjacent CO group, followed by cyclization and dehydration.